Results 51 to 60 of about 77,370 (304)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Beware of hemopneumothorax following core needle breast biopsy

Respiratory Medicine Case Reports, 2018
Minimal diagnostic procedures are conducted regularly by the radiologists for several lesions within the body. The usual methodology is biopsy with a needle, either fine needle aspiration or core biopsy. The guidance is under CT or U/S.
Nikos Schizas, Achileas Lazopoulos, Dimitris Krimiotis, Thomas Rallis, Dimitris Paliouras, Apostolos Gogakos, Fotis Chatzinikolaou, Pavlos Sarafis, Philip Domeyer, Paul Zarogoulidis, Theodora Tsiouda, Chrysanthi Sardeli, Stella Laskou, Charilaos Koulouris, Efstathios Pavlidis, Stylianos Mantalobas, Dimitris Giannakidis, Isaak Kesisoglou, Konstantinos Sapalidis, Nikos Barbetakis   +19 more
doaj   +1 more source

Ask a pathologist [PDF]

, 2013
QUESTION: My patient has a palpable neck mass that is suspicious for malignancy, and I am considering ordering a fine needle aspiration (FNA) versus a core needle or open biopsy.
Coberly, Emily, Esebua, Magda
core  

Percutaneous Biopsy of the Renal Mass: Fine Needle Aspiration or Core Biopsy? [PDF]

, 2017
BACKGROUND In recent years, there have been increasing indications for percutaneous renal biopsy. Fine-needle aspiration (FNA), with or without core needle biopsy (CB), has been used increasingly in the management of renal tumors at the study ...
Chen, Shaoxiong, Choi, Euna, Idrees, Muhammad, Wu, Howard H., Yang, Chi-Shun   +4 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study

Diagnostics, 2021
Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) or biopsy (FNB) to diagnose lesions in the gastrointestinal tract is common. Demand for histology sampling to identify treatment-specific targets is increasing. Various core biopsy FNB needles
Geke Litjens, Christian Gerges, Yogesh M. Shastri, Piyush Somani, Torsten Beyna, Horst Neuhaus, Cornelis J. H. M. van Laarhoven, Mathias Prokop, Peter D. Siersema, John J. Hermans, Erwin J. M. van Geenen   +10 more
doaj   +1 more source

An Open-Source 7-Axis, Robotic Platform to Enable Dexterous Procedures within CT Scanners

, 2019
This paper describes the design, manufacture, and performance of a highly dexterous, low-profile, 7 Degree-of-Freedom (DOF) robotic arm for CT-guided percutaneous needle biopsy.
Norbash, Alexander M., Schreiber, Dimitri A., Shak, Daniel B., Yip, Michael C.   +3 more
core   +1 more source

Delayed phlegmon with gallstone fragments masquerading as soft tissue sarcoma. [PDF]

, 2016
Complications from lost gallstones after cholecystectomy are rare but varied from simple perihepatic abscess to empyema and expectoration of gallstones.
Bateni, Cyrus P, Bishop, John W, Canter, Robert J, Goodman, Laura F   +3 more
core   +1 more source

Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics

Advanced Functional Materials, EarlyView.
Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha, Ju Yeon Chung, Seungju Yang, Seung Cheol Lee, Chan Woo Lee, Colin Wing‐Lok Cheng, Jun Beom Kim, Nam Jun Kim, Ayoung Park, Heewon Choi, Junpyo Sinn, Ralph Weissleder, Nicholas A. Kotov, Myungeun Seo, Hyun Jung Chung, Sang Ouk Kim   +15 more
wiley   +1 more source