Results 91 to 100 of about 2,117,779 (343)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Core melt stabilization (COMESTA)
, 2009 COMESTA project has investigated core melt behavior in a severe accident. Experiments have been conducted both at VTT and in international projects on the subjects of molten core - concrete interactions, melt pool coolability and steam explosions. Competence for computational modeling of severe accidents has been developed.
Sevon Tuomo, Lindholm Ilona
openaire +4 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
The core-periphery model with three regions [PDF]
We study a 3-region core-periphery model à la Krugman and compare our results with those of the standard 2-region model. The conditions for the stability of the dispersion and concentration configurations are established.
Joao Correia-da-Silva +2 more
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The Stability of the Roommate Problem Revisited [PDF]
The lack of stability in some matching problems suggests that alternative solution concepts to the core might be applied to find predictable matchings. We propose the absorbing sets as a solution for the class of roommate problems with strict preferences.
Iñarra García, María Elena +2 more
core
Relationship Between Cycling Mechanics and Core Stability
The Journal of Strength and Conditioning Research, 2007 Core stability has received considerable attention with regards to functional training in sports. Core stability provides the foundation from which power is generated in cycling. No research has described the relationship between core stability and cycling mechanics of the lower extremity.
John P, Abt +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Kısa mesafe koşucuları ve basketbolcularda kor stabilite ve atletik performans arasındaki ilişki
Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2018 Bu çalışmanın amacı 14-16 yaş grubu elit erkek kısa mesafe koşucuları ve basketbolcularda kor stabilite ve atletik performans arasındaki ilişkiyi incelemek ve karşılaştırmaktı. Çalışmaya 16 erkek kısa mesafe koşucusu (yaş 14,18 ± 0,94 yıl, boy 166,50 ± 8,
Okan Kamiş, H. Ahmet Pekel, Latif Aydos
doaj +1 more source