Results 121 to 130 of about 2,117,779 (343)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

An explanation of the instability of the free vortex cores occurring over delta winds with raised edges [PDF]

open access: yes
By rolling up the surfaces of discontinuity originating from the leading edge of delta wings, free vortex cores are formed above the wing. In case of greater angles of incidence, the flow in these vortex cores shows an instability which abruptly produces
Ludwieg, H.
core   +1 more source

Dense core formation in supersonic turbulent converging flows

open access: yes, 2011
We use numerical hydrodynamic simulations to investigate prestellar core formation in the dynamic environment of giant molecular clouds, focusing on planar post-shock layers produced by colliding turbulent flows.
André   +74 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

The Relationship Between Core Stability and Leg Stiffness in Male and Female Athletes

open access: yesPhysical Treatments, 2016
Purpose: Core stability and leg stiffness are two determinant mechanisms in athletic performance and risk injury. This study aimed to investigate the gender differences and relationship of these two factors in athletes.
Mojtaba Ashrostaghi   +2 more
doaj  

Computational Complexity in Additive Hedonic Games [PDF]

open access: yes
We investigate the computational complexity of several decision problems in hedonic coalition formation games and demonstrate that attaining stability in such games remains NP-hard even when they are additive.
Dinko Dimitrov, Shao-Chin Sung
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

How should central banks define price stability? [PDF]

open access: yes
It is now generally accepted that the primary objective of central banks should be the maintenance of price stability. This paper considers the question of how central banks should define price stability. I address three specific questions. First, should
Mark A. Wynne
core  

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