Results 241 to 250 of about 410,180 (300)

Artificial Intelligence-Driven Inverse Design of Singlet Fission Candidates in the Acene family. [PDF]

open access: yesAdv Sci (Weinh)
Uceda RG   +9 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Impact of Biopsy-to-Radical Prostatectomy Interval on Adverse Pathological Outcomes in High-Risk Localized and Locally Advanced Prostate Cancer. [PDF]

open access: yesDiagnostics (Basel)
Reman LT   +11 more
europepmc   +1 more source

Multi-sampling allows intra-tumoral heterogeneity querying and vulnerability profiling in glioblastoma. [PDF]

open access: yesNeuro Oncol
Garcia DM   +14 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy