Results 171 to 180 of about 261,489 (296)

Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates

open access: yesThe FEBS Journal, EarlyView.
In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi   +6 more
wiley   +1 more source

Analysis of the suitability for ecotourism in Beira Baixa region using a spatial decision support system based on a geographical information system

open access: yesRegional Science Policy &Practice, EarlyView., 2022
Abstract Ecotourism can contribute to the conservation of environmental values, as well as to the development of positive synergies between agents in the tourism sector, tourists and the local population. The growing interest in tourism offers with low environmental impact, which support the local economy, translates into a competitive advantage for ...
Luís Quinta‐Nova, Dora Ferreira
wiley   +1 more source

Development and Validation of a Food Frequency Questionnaire to Assess Fermented Food Consumption in Adults. [PDF]

open access: yesJ Hum Nutr Diet
Ferri A   +7 more
europepmc   +1 more source

The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione

open access: yesThe FEBS Journal, EarlyView.
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper   +8 more
wiley   +1 more source

Metabolic Health Phenotypes Among Middle‐ to Older‐Aged Adults Living With and Without Obesity: Relationships With Hepatic Health Indicators

open access: yesHepatology Research, EarlyView.
We examined liver health indicators among obese and nonobese metabolic health phenotypes. In fully adjusted models, higher fatty liver index (FLI) scores and liver enzyme concentrations of gamma‐glutamyl transferase (GGT) and alanine aminotransferase (ALT) were associated with lower likelihood of metabolically healthy obese (MHO) and nonobese (MHNO ...
Grainne Dolan   +3 more
wiley   +1 more source

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