‘Carbon-Monoxide-Releasing Molecule-2 (CORM-2)’ Is a Misnomer: Ruthenium Toxicity, Not CO Release, Accounts for Its Antimicrobial Effects [PDF]
Antioxidants, 2021 Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological ‘gasotransmitter’, in biological chemistry and biomedicine. CORMs kill bacteria in culture and in animal models, but are reportedly benign towards mammalian cells. CORM-
Hannah M Southam +2 more
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CORM-2-entrapped ultradeformable liposomes ameliorate acute skin inflammation in an ear edema model via effective CO delivery [PDF]
Acta Pharmaceutica Sinica B, 2020 The short release half-life of carbon monoxide (CO) is a major obstacle to the effective therapeutic use of carbon monoxide-releasing molecule-2 (CORM-2).
Alam Zeb, Eun-Hye Kim, Young-Jun Shin
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CORM-2 Pretreatment Attenuates Inflammation-mediated Islet Dysfunction [PDF]
Cell Transplantation, 2020 During the process of human islet isolation a cascade of stressful events are triggered and negatively influence islet yield, viability, and function, including the production of proinflammatory cytokines and activation of apoptosis.
Xiang-Heng Cai +9 more
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The role of CORM-2 as a modulator of oxidative stress and hemostatic parameters of human plasma in vitro. [PDF]
PLoS ONE, 2017 The main aim of the experiment is to examine the effect of CORM-2, a donor of carbon monoxide (CO), on oxidative stress in human plasma in vitro. In addition, it examines the effects of CORM-2 on the hemostatic parameters of plasma: the activated partial
Weronika Adach, Beata Olas
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Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice. [PDF]
PLoS ONE, 2018 The antinociceptive effects of the carbon monoxide-releasing molecule tricarbonyldichlororuthenium (II) dimer (CORM-2) during chronic pain are well documented, but most of its possible side-effects remain poorly understood.
Karen Alejandra Méndez-Lara +12 more
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CORM‑2 reduces cisplatin accumulation in the mouse inner ear and protects against cisplatin-induced ototoxicity [PDF]
Journal of Advanced ResearchMin Jung Park, Yong-Ho Park
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Global gene expression profiling and antibiotic susceptibility after repeated exposure to the carbon monoxide-releasing molecule-2 (CORM-2) in multidrug-resistant ESBL-producing uropathogenic Escherichia coli. [PDF]
PLoS ONE, 2017 Treatment of urinary tract infections is today a challenge due to the increasing prevalence of multidrug-resistant ESBL-producing uropathogenic Escherichia coli (UPEC). There is an urgent need for new treatment strategies for multidrug-resistant UPEC and
Charlotte Sahlberg Bang +3 more
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Effect of mother corm weight and foliar application of nutrients on flower and corm yield of Spanish and Iranian saffron (Crocus sativus L.) [PDF]
Zirā̒at va Fanāvarī-i Za̒farān, 2017 The corm size, nutrient management and corm type are the most important factors that may affect the quantitative and qualitative characteristics of saffron (Crocus sativus L.).
hossein sahabi +3 more
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Evaluation of saffron flower and corm yield affected by different maternal corm weight and sowing depth [PDF]
Zirā̒at va Fanāvarī-i Za̒farān, 2019 In order to study the effects of different weights of mother corm and sowing depth on flower and corm yield of saffron (Crocus sativus L.), an experiment was conducted as a factorial layout based on complete randomized block design with three ...
Mohsen Razavian +2 more
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Effects of maternal corm weight and different levels of cow manure on corm and flower yield of saffron (Crocus sativus L.) [PDF]
Zirā̒at va Fanāvarī-i Za̒farān, 2013 In order to investigate the effects of different maternal corm weight and different levels of cow manure on saffron (Crocus sativus L.) production, an experiment was conducted at the Agricultural Research Station, Ferdowsi University of Mashhad during ...
fatemeh Hassanzadeh Aval +3 more
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