Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Transcriptome sequencing reveals iron acquisition-related genes and iron acquisition systems in Auricularia cornea. [PDF]
Zhu Q +7 more
europepmc +1 more source
Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo +4 more
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Myogenic Differentiation (MyoD) Gene Expression in Cornea and Role in Corneal Myofibroblast Dedifferentiation. [PDF]
Tripathi R +9 more
europepmc +1 more source
Anterior Segment Optical Coherence Tomography with Angiography for the Cornea and Ocular Surface. [PDF]
Wong QY, Sim R, Ang M.
europepmc +1 more source
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is commonly framed as a corneal endothelial disease characterised by guttae accumulation and progressive thickening of Descemet's membrane (DM). However, clinical forms and evolutionary profiles vary widely.
Sayo Maeno +3 more
wiley +1 more source
A rare case of musculocontractural Ehler-Danlos syndrome with cornea plana and juvenile glaucoma. [PDF]
Manapakkam M +2 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo +3 more
wiley +1 more source
Intercellular forces driving stratification in a two-layer corneal epithelium: Insight from a Voronoi cell-based simulation model. [PDF]
Khodabakhsh Joniani N +3 more
europepmc +1 more source

