Results 31 to 40 of about 1,419 (159)
Homozygous familial hypercholesterolemia associated with symmetric subcutaneous lipomatosis
Indian Journal of Dermatology, 2015 Homozygous familial hypercholesterolemia is an autosomal dominant disorder of lipid metabolism, characterized by reduced clearance of low-density lipoprotein-cholesterol and a high risk of rapid development of cardiovascular diseases.
Noha Mohammed Dawoud +2 more
doaj +1 more source
Journal of Clinical and Basic Research, 2017 Introduction: Corneal arcus caused by lipid deposition around the cornea has been proposed as an early marker for several metabolic disorders and even cardiovascular events.
Negar Broomand +3 more
doaj +2 more sources
Xanthelasma palpebrarum with arcus cornea: A clinical and biochemical study
Indian Journal of Dermatology, 2016 Background: Xanthelasma palpebrarum (XP) is characterized by sharply demarcated yellowish flat plaques on upper and lower eyelids. It is commonly seen in women with a peak incidence at 30–50 years.
Pragya Ashok Nair +4 more
doaj +1 more source
PCSK9 Inhibitors Reduce Oxidative Stress Biomarkers in Heterozygous Familial Hypercholesterolemia
Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.ABSTRACT Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, such as alirocumab and evolocumab, effectively reduce LDL‐C levels, improve cardiovascular outcomes, and are well tolerated in the treatment of heterozygous familial hypercholesterolemia (HeFH).
Agnieszka Woźniak‐Szczepocka +5 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Heterozygous familial hypercholesterolemia (HeFH) more likely exhibits extensive atherosclerotic disease at multiple vascular beds. Lipoprotein(a) (Lp(a)) is an atherogenic lipoprotein that elevates HeFH‐related atherosclerotic cardiovascular ...
Sayaka Funabashi +6 more
doaj +1 more source
First LDLRAP1 and Recurrent LDLR Mutations in Tunisian Families With Familial Hypercholesterolemia
Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.ABSTRACT Familial hypercholesterolemia (FH) is a genetic disorder characterised by elevated plasma LDL‐cholesterol, predisposing to premature atherosclerotic cardiovascular disease. Most cases follow an autosomal dominant pattern (ADH) caused by pathogenic variants in LDLR, APOB or PCSK9.
Wirath Ben Ncir +9 more
wiley +1 more source
Influence of brightness artefacts on corneal densitometry
Ophthalmic and Physiological Optics, Volume 45, Issue 3, Page 637-643, May 2025.Abstract Purpose To quantify objectively the influence of brightness artefacts inherent in Scheimpflug tomography on corneal densitometry (CD) estimates. Methods Fifty‐seven healthy participants aged 30.9 ± 13.7 years (range 17–60 years) were examined with a Ziemer Galilei G2 Scheimpflug tomographer.
Ana R. Arizcuren +2 more
wiley +1 more source
Susac′s syndrome: First from India and youngest in the world
Indian Journal of Ophthalmology, 2013 A two and half year old female was admitted at the emergency room suffering from gradually worsening headache followed by nausea. The child presented with reduced level of consciousness and bilateral hypoacusis. The patient was lethargic.
Gunjan Prakash +3 more
doaj +1 more source
Health Science Reports, Volume 8, Issue 3, March 2025.ABSTRACT Background and Aims Familial hypercholesterolemia (FH) is a substantial contributor to the development of atherosclerotic cardiovascular disease. Therefore, the primary focus of our study was to examine sex‐based disparities in clinical signs, atherosclerotic status, lipid profiles, and treatment intensity among patients with FH from Vietnam ...
Ngoc‐Thanh Kim +5 more
wiley +1 more source
Double arcus cornealis: A case report
Indian Journal of Ophthalmology. Case ReportsThe corneal arcus is a degenerative change that involves lipid deposition and presents as a white circumferential band located in the peripheral cornea.
Pragati Garg +3 more
doaj +1 more source