Results 101 to 110 of about 171,373 (375)
Advanced Science, Volume 12, Issue 11, March 20, 2025.This article demonstrates that the peptide bxyPenetratin (bxyWP) non‐covalently binds to the anti‐vascular endothelial growth factor (VEGF) protein aflibercept via hydrophobic interactions, enabling noninvasive delivery of aflibercept to the choroid and retina through conjunctival‐scleral pathway and effective inhibition of choroidal neovascularization
Xingyan Fan +7 more
wiley +1 more source
Epilepsia Open, EarlyView., 2022 Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski +3 more
wiley +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.A new series of highly potent dipeptidic phosphonates targeting the Pseudomonas aeruginosa protease LasB shows promising in vitro effects, favorable pharmacokinetics, good tolerability, and in vivo efficacy, highlighting their potential as a treatment for Pseudomonas keratitis when combined with meropenem. Abstract The ubiquitous opportunistic pathogen
Alexander F. Kiefer +22 more
wiley +1 more source
Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]
, 2004 Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Jayasekera, S. +4 more
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The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. [PDF]
, 2020 Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular immune response comprising innate and adaptive phases. When the ocular immune system is excessively stimulated and/or immunoregulatory mechanisms are disrupted, the ...
Lin, Meng C +4 more
core +1 more source
The variability of corneal and anterior segment parameters in keratoconus [PDF]
, 2016 Purpose: To analyse, describe and test diverse corneal and anterior segment parameters in normal and keratoconic eyes to better understand the geometry of the keratoconic cornea. Method: 44 eyes from 44 keratoconic patients and 44 eyes from 44 healthy
Cardona Torradeflot, Genís +3 more
core +1 more source
Microneedles at the Forefront of Next Generation Theranostics
Advanced Science, EarlyView.The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang +8 more
wiley +1 more source
Corneal reflex in hemisphere disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1972 The contralateral corneal reflex may be absent in patients with a deep lesion of the parietal lobe. Frontal and temporal lobe lesions apparently do not interfere with this reflex.
openaire +3 more sources