Corneal nerves in health and disease [PDF]
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to maintain transparency and contribute to corneal health by mediating tear secretion and protective reflexes and provide trophic support to epithelial and stromal cells.
Mouhamed A. Al-Aqaba +4 more
openaire +4 more sources
Corneal Disease & Transplantation. [PDF]
Corneal diseases represent the third leading cause of blindness worldwide, and corneal transplantation, which aims at restoring corneal clarity and vision, is the most frequently performed transplant worldwide [...]
Coco G, Romano V.
europepmc +6 more sources
Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]
Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J. +34 more
core +5 more sources
Corneal Opacity in LCAT Disease [PDF]
Deficiency of lecithin:cholesterol acyltransferase, LCAT disease, is one of the dyslipoproteinemias with characteristic lipid deposits in the cornea. The present report documents the clinicopathologic abnormalities of one case in which a full-thickness corneal specimen was obtained at the time of corneal transplantation.
Cogan, David G. +3 more
openaire +2 more sources
Corneal diseases are common in domestic rabbits. It is important to carefully evaluate the cornea and the entire eye when rabbit present with clinical signs such as squinting, tearing, or conjunctival hyperemia. Complete ophthalmic examination and general physical examination should be performed on all rabbits with corneal disease. Important diagnostic
Department of Comparative Ophthalmology, Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100126, Gainesville, FL 32610-0126, USA ( host institution ) +1 more
openaire +3 more sources
Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]
Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Khan, Naveed Ahmed +4 more
core +5 more sources
Evaluation of interface quality in organ-cultured lamellar corneal transplants [PDF]
Background: With increasing numbers of lamellar keratoplasties, eye banks are challenged to deliver precut lamellar donor tissue. In Europe, the most common technique of corneal storage is organ culture which requires a deswelling process before surgical
Kohnen, Thomas +7 more
core +1 more source
Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: Expression, design optimization, uptake mechanism and nuclear localization [PDF]
Copyright © The Author 2009. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses?by-nc/2.0/uk/) which permits ...
Seow, WY, George, AJT, Yang, Y-Y
core +1 more source
Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J +59 more
core +1 more source
Topical rosiglitazone is an effective anti-scarring agent in the cornea [PDF]
Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome ...
Phipps, Richard P. +17 more
core +2 more sources

