Results 211 to 220 of about 94,278 (287)

SIRT1 Prevents Lens Epithelial Cell Senescence During Age‐Related Cataract via Regulating p66Shc

open access: yesAging Cell, EarlyView.
Schematic illustration of NMN‐mediated alleviation of age‐related cataract via SIRT1/p66Shc pathway–dependent inhibition of mitochondrial dysfunction and LEC senescence. ABSTRACT Lens epithelial cell (LEC) senescence is one of the key pathological processes of age‐related cataract (ARC) and is associated with oxidative stress, mitochondrial dysfunction,
Huirui Liu   +8 more
wiley   +1 more source

Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment

open access: yesAging Cell, EarlyView.
Local growth hormone (GH) is expressed and secreted by senescent cells in the aging human colon. GH triggers epithelial‐to‐mesenchymal transition and activates colon cell motility by regulating extracellular matrix proteins, inducing cytoskeleton rearrangement and altering cell motility protein phosphorylation.
Vera Chesnokova   +8 more
wiley   +1 more source

The Role of Scalp EEG Recordings During Cortical Visual Prosthesis Testing

open access: yesArtificial Organs, EarlyView.
This article describes the role of recording scalp EEG for projects that are developing cortical visual prosthesis systems. It concludes that EEG is not required during basic threshold and spatial mapping studies, but should be considered when higher levels of stimulation and video‐camera stimulation are employed.
Katarina Stephan   +13 more
wiley   +1 more source

Two‐year changes of macular choroidal thickness in response to 0.01% atropine eye drops: Results from the myopia outcome study of atropine in children (MOSAIC) clinical trial

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate 2‐year changes in macular choroidal thickness (ChT) in children receiving 0.01% atropine eyedrops and its relationship with spherical equivalent refraction (SER) progression and axial length (AL) elongation. Methods A total of 250 myopic children aged 6–16 years (167%–0.01% atropine, 83‐placebo) were enrolled in the ...
Emmanuel Kobia‐Acquah   +3 more
wiley   +1 more source

Effects of customized corneal cross‐linking on higher‐order aberrations in progressive keratoconus and low‐grade myopia

open access: yesActa Ophthalmologica, EarlyView.
Abstract Objective To evaluate the effects of customized corneal collagen cross‐linking (CXL) on higher‐order aberrations (HOAs) in keratoconus (KC): vertical coma (VC), horizontal coma (HC), spherical aberration (SA), trefoil (TF) and astigmatism, compared with the same effects in healthy eyes undergoing CXL for low‐grade myopia.
Jad Hayek   +4 more
wiley   +1 more source

Is corneal arcus an independent predictor of incident cardiovascular disease?

open access: bronze, 2017
Mark Yu Zheng Wong   +7 more
openalex   +1 more source

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