Results 231 to 240 of about 102,606 (291)

A Novel Homozygous Nonsense Pathogenic Variant of the CPAMD8 Gene Associated With Congenital Microcoria

Clinical Genetics, EarlyView.
A novel CPAMD8 nonsense mutation c.2679C>G (p.Tyr893*) was identified in a patient with congenital microcoria, leading to reduced mRNA expression and predicted protein truncation. ABSTRACT Congenital microcoria (MCOR) is a rare inherited ocular disorder. Here, we describe a novel nonsense variant in the CPAMD8 gene in a patient with MCOR.
Jing‐Fan Gao, Xin Jin, Jing‐Rao Wang, Shu Wang, Hong Zhang   +4 more
wiley   +1 more source

Ocular surface health and disease: insight from single-cell RNA sequencing. [PDF]

Front Genet
Ou S, Cai M, Feng Y, Lin S, Zheng X, Zhao S, Gu H, Wu Y.   +7 more
europepmc   +1 more source

Adhesion of Immunoglobulins to Band3 Promotes Increased Erythrocyte Sedimentation Rate in Multiple Myeloma

Cell Proliferation, EarlyView.
Decreased sialic acid increases the adhesion of RBC membranes to immunoglobulins leading to an increased erythrocyte sedimentation rate (ESR). The increase in reactive oxygen species (ROS) damages the sialic acid glycosyl chains on the surface of RBC membrane proteins, causing the membrane proteins to be overexposed to the plasma environment due to the
Sicheng Bian, Jiangxia Cui, Xialin Zhang, Chongzhi Bai, Yanhong Tan, Zhuanghui Hao, Xingpeng Bu, Changxin Qu, Lili Sun, Leilei Lin, Qi Wang, Zhengrui Li, Xufeng Huang, Hengrui Liu, Ruo Wang, Yinghua Li, Hongwei Wang   +16 more
wiley   +1 more source

Outcome of Allogeneic Penetrating Limbo-Keratoplasty: A Single-Center Retrospective Cohort Study. [PDF]

J Clin Med
Horstmann ME, Schuster AK, Pfeiffer N, Wasielica-Poslednik J.   +3 more
europepmc   +1 more source

Imaging Approaches for the Diagnosis of Dry Eye: A Review. [PDF]

Diagnostics (Basel)
Macri A, Tarallo M, Iester M.
europepmc   +1 more source

Correlation analysis of the copy number of aqueous humor HSV DNA with anterior chamber reaction, topical steroid responsiveness and prognosis of endothelial herpes simplex keratitis. [PDF]

BMC Ophthalmol
Yang J.
europepmc   +1 more source

Acute corneal epithelial debridement in rats unmasks the corneal stromal nerve responses to ocular stimulation: Implications for abnormal sensations in recurrent corneal erosion and dry eye disease.

, 2017
Harumitsu Hirata, Kamila Mizerska, Valentina Dallacasagrande, Victor H. Guaiquil, Mark I. Rosenblatt   +4 more
openalex   +1 more source

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches

Developing World Bioethics, EarlyView.
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley   +1 more source

Netarsudil and Corneal Edema: An Update and Review of the Literature. [PDF]

Clin Ophthalmol
Troup DC, Chauhan MZ, Guo Z, Sanvicente CT, Warner DB, Sallam AB.   +5 more
europepmc   +1 more source

Continuous glucose monitoring and microvascular complications in diabetes: Bridging glycemic metrics with clinical outcomes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Continuous glucose monitoring (CGM) has emerged as a complementary and more dynamic method for evaluating glycemic control in people with diabetes. Relevant studies examining the association between CGM parameters, including time in range (TIR), glycemic variability (GV), and time in tight range (TITR), and diabetic nephropathy, retinopathy ...
Lilian Anagnostopoulou, Alexandros L. Liarakos, Ioannis Ntanasis‐Stathopoulos, Alexandros Briasoulis, Anastasios Tentolouris   +4 more
wiley   +1 more source