Results 71 to 80 of about 5,036,145 (299)

Bilateral corneal ulceration in ocular graft-versus-host disease

open access: yes, 2013
William Stevenson, Hasanain Shikari, Ujwala S Saboo, Francisco Amparo, Reza Dana Cornea Service, Massachusetts Eye and Ear Infirmary, Boston, MA, USA Purpose: To report on corneal ulceration in ocular graft-versus-host disease (GVHD). Methods: This was a
Dana R   +4 more
core  

Corneal Dermoid [PDF]

open access: yes, 2011
A 20 years old boy presented with left corneal mass. The mass involved entire cornea extending to the sclera. The mass had a skin like surface and protruded outside the palpebral aperture.
Kudva, AA, Hegde, S, Kadri, R, Achar, A
core  

Surgery versus epilation for the treatment of minor trichiasis in Ethiopia: a randomised controlled noninferiority trial. [PDF]

open access: yes, 2011
Trachomatous trichiasis can cause corneal damage and visual impairment. WHO recommends surgery for all cases. However, in many regions surgical provision is inadequate and patients frequently decline.
Saul N. Rajak   +55 more
core   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Long-Term Clinical Outcomes of nDSAEK and Machine Learning-Based Prediction of Graft Survival in Corneal Endothelial Decompensation

open access: yesClinical Ophthalmology
Yuan Lin,1– 6,* Yiming Hu,7,* Zhiwen Xie,1– 6,* Xie Fang,1– 6 Shunrong Luo,1– 6 Xianwen Xiao,1– 6 Zhirong Lin,1– 6 Huping Wu1– 6 1Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, People’s ...
Lin Y   +7 more
doaj  

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

ADVERTISEMENT ALLERGAN

open access: yesVision Pan-America, 2017
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Paulo E.C. Dantas
doaj   +1 more source

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

open access: yesAdvanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong   +7 more
wiley   +1 more source

Book Review

open access: yesVision Pan-America, 2015
“How to get started with Standardized ‘No-Touch’ DMEK” by Gerrit Melles and Isabel Dapena is the first text book in literature describing this relatively new surgical procedure in detail: Descemet membrane endothelial keratoplasty.
Paulo E.C. Dantas
doaj   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin   +7 more
wiley   +1 more source

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