Results 121 to 130 of about 9,215,935 (380)

Identifying factors associated with fast visual field progression in patients with ocular hypertension based on unsupervised machine learning [PDF]

open access: yesarXiv, 2023
Purpose: To identify ocular hypertension (OHT) subtypes with different trends of visual field (VF) progression based on unsupervised machine learning and to discover factors associated with fast VF progression. Participants: A total of 3133 eyes of 1568 ocular hypertension treatment study (OHTS) participants with at least five follow-up VF tests were ...
arxiv  

Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]

open access: yes, 2018
Purpose: To evaluate the safety and efficacy of topical recombinant human nerve growth factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare degenerative corneal disease resulting from impaired corneal innervation.
Alio, Jorge   +45 more
core   +1 more source

NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin‐Binding Integrins

open access: yesAdvanced Science, EarlyView.
Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso   +9 more
wiley   +1 more source

Use of topical tacrolimus in ophthalmology: Nonsystematic review

open access: yesThe Pan-American Journal of Ophthalmology, 2020
The two immunosuppressants most used topically in ophthalmology are cyclosporine (CS) and tacrolimus (TL). Their mechanism of action is similar, but the TL is ten to a hundred times more powerful than the CS.
Morgana Arima Vedovato   +6 more
doaj   +1 more source

Causes of congenital corneal opacities and their management in a tertiary care center. [PDF]

open access: yes, 2020
PURPOSE: To evaluate causes and management of congenital corneal opacities (CCO) diagnosed in a tertiary care eye center and to compare the data with a previous study at the same institution.
Hammersmith, Kristin M   +3 more
core   +1 more source

Vascular endothelial growth factor (VEGF) serological and lacrimal signaling in patients affected by vernal keratoconjunctivitis (VKC) [PDF]

open access: yes, 2018
Background. Vernal keratoconjunctivitis (VKC) is a rare inflammatory disease involving the ocular surface, with seasonally exacerbated symptoms. Both type-1 and type-4 hypersensitivity reactions play a role in the development of VKC. Purpose.
Aventaggiato, Michele   +5 more
core   +1 more source

ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

open access: yesAdvanced Science, Volume 12, Issue 16, April 24, 2025.
A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu   +10 more
wiley   +1 more source

Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]

open access: yes, 2016
BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S.   +5 more
core  

Acanthamoeba induces cell-cycle arrest in host cells [PDF]

open access: yes, 2004
Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alizadeh   +41 more
core   +1 more source

Age distribution of various corneal diseases in China by histopathological examination of 3112 surgical specimens.

open access: yesInvestigative Ophthalmology and Visual Science, 2014
PURPOSE To analyze the age distribution of corneal disease in China by histopathological examination. METHODS A retrospective histopathological analysis of the prevalence and age distribution of corneal disease was performed on corneal specimens from ...
Xiaohua Li   +3 more
semanticscholar   +1 more source

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