Results 121 to 130 of about 9,215,935 (380)
Identifying factors associated with fast visual field progression in patients with ocular hypertension based on unsupervised machine learning [PDF]
arXiv, 2023 Purpose: To identify ocular hypertension (OHT) subtypes with different trends of visual field (VF) progression based on unsupervised machine learning and to discover factors associated with fast VF progression. Participants: A total of 3133 eyes of 1568 ocular hypertension treatment study (OHTS) participants with at least five follow-up VF tests were ...
arxiv
Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
, 2018 Purpose: To evaluate the safety and efficacy of topical recombinant human nerve growth factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare degenerative corneal disease resulting from impaired corneal innervation.
Alio, Jorge +45 more
core +1 more source
Advanced Science, EarlyView.Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso +9 more
wiley +1 more source
Use of topical tacrolimus in ophthalmology: Nonsystematic review
The Pan-American Journal of Ophthalmology, 2020 The two immunosuppressants most used topically in ophthalmology are cyclosporine (CS) and tacrolimus (TL). Their mechanism of action is similar, but the TL is ten to a hundred times more powerful than the CS.
Morgana Arima Vedovato +6 more
doaj +1 more source
Causes of congenital corneal opacities and their management in a tertiary care center. [PDF]
, 2020 PURPOSE: To evaluate causes and management of congenital corneal opacities (CCO) diagnosed in a tertiary care eye center and to compare the data with a previous study at the same institution.
Hammersmith, Kristin M +3 more
core +1 more source
Vascular endothelial growth factor (VEGF) serological and lacrimal signaling in patients affected by vernal keratoconjunctivitis (VKC) [PDF]
, 2018 Background. Vernal keratoconjunctivitis (VKC) is a rare inflammatory disease involving the ocular surface, with seasonally exacerbated symptoms. Both type-1 and type-4 hypersensitivity reactions play a role in the development of VKC. Purpose.
Aventaggiato, Michele +5 more
core +1 more source
Advanced Science, Volume 12, Issue 16, April 24, 2025.A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu +10 more
wiley +1 more source
Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]
, 2016 BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S. +5 more
core
Acanthamoeba induces cell-cycle arrest in host cells [PDF]
, 2004 Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alizadeh +41 more
core +1 more source
Investigative Ophthalmology and Visual Science, 2014 PURPOSE To analyze the age distribution of corneal disease in China by histopathological examination. METHODS A retrospective histopathological analysis of the prevalence and age distribution of corneal disease was performed on corneal specimens from ...
Xiaohua Li +3 more
semanticscholar +1 more source