Results 121 to 130 of about 135,122 (302)

Two Central Nervous System Tumors in One Catheter Lab: Time to Rethink Radiation Protection

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Very little research has been done on the possible effects that repeated, frequent, and low‐dose ionizing radiation exposure has on the long‐term health of interventional cardiologists. Aims Following the diagnosis in the same year of two central nervous system tumors in two operators working in the same catheter laboratory, we ...
James R. Bentham, John D. R. Thomson
wiley   +1 more source

Ranking of antiseizure medications in a panel of focal seizure models predicts their comparative efficacy in clinical add‐on trials in drug‐resistant focal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Most antiseizure medications (ASMs) have been discovered by testing in animal models, which are generally thought to predict antiseizure activity in patients. However, it is not known whether any of these models (or a combination of models) can predict whether a novel ASM exhibits higher clinical efficacy in focal drug‐resistant ...
Wolfgang Löscher, Pavel Klein
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Differences in localization of P2X7 during epithelial wound healing in pre-type II diabetic models [PDF]

open access: yes, 2017
Corneal injury, accompanied by improper wound repair, is the 4th highest cause of preventable blindness according to the World Health Organization.
Kneer, Krisandra
core  

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape   +3 more
wiley   +1 more source

Artificial Intelligence in Ophthalmology: Current Status, Challenges, and Future Perspectives

open access: yesHealth Care Science, EarlyView.
Current research of artificial intelligence (AI) in ophthalmology. ABSTRACT Artificial intelligence (AI) is revolutionizing ophthalmology by providing innovative solutions for disease screening, diagnosis, personalized treatment, and the delivery of global healthcare services.
She Chongyang, Tao Yong
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

A Case Report on use of Topical Insulin Therapy for Persistent Epithelial Defects in Stevens-Johnson Syndrome

open access: yesJournal of Clinical and Diagnostic Research
Persistent Epithelial Defects (PED) in Stevens-Johnson Syndrome (SJS) pose significant challenges in ophthalmic management. This case highlights the use of topical insulin therapy as a novel treatment for PED in a 59-year-old female with SJS-associated ...
Sumit Navneet Toshniwal   +3 more
doaj   +1 more source

Comparative Evaluation of Four Stereotactic Radiosurgery Planning Approaches for Treatment of Posterior Choroidal Melanoma

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This study evaluated four stereotactic radiosurgery planning approaches for posterior choroidal melanoma (CM). Analysis of thirteen CM cases resulted in a clinically meaningful reduction in dose to the brain for Brainlab Elements modulated arcs (BE) and Varian Eclipse HyperArc modulated arcs (HA) compared to Brainlab iPlan dynamic conformal arc therapy
Robert Nigro   +5 more
wiley   +1 more source

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