Results 211 to 220 of about 9,423,348 (360)

Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications

open access: yesChemBioChem, EarlyView.
Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres   +7 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Mini Review: Current Trends and Understanding of Exosome Therapeutic Potential in Corneal Diseases. [PDF]

open access: yesFront Pharmacol, 2021
Tiwari A   +5 more
europepmc   +1 more source

Research on the Distribution Law of Air Flow and Dust in Multi‐Process Operations of Coal Mine Fully Mechanized Caving Face

open access: yesEnergy Science &Engineering, EarlyView.
ABSTRACT The aim of this study is to examine the intricate dynamics involved in the production, movement, and settling of dust particles, as well as the interconnected mechanisms at play during various processes within fully automated coal mining fronts.
Yibo Li   +5 more
wiley   +1 more source

Ex-Ante Evaluation of Nutrition and Health Benefits of Biofortified Cassava Roots in Nigeria: The Dalys Approach [PDF]

open access: yes
Cassava is a major staple that supplies more than 50% of daily energy to more than 200 million persons in sub-Saharan Africa (SSA). Cassava roots are known to be low in micronutrients such as vitamin A, iron, and zinc. Micronutrient deficiencies threaten
Awotide, D.O.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy