Results 251 to 260 of about 9,215,935 (380)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Preparation of Collagen Peptide Nanoliposomes From Sturgeon Fish Cartilage and Explore Their Anti‐Osteoarthritis Effects in Rats

open access: yesFood Frontiers, Volume 6, Issue 2, Page 727-749, March 2025.
This study aims to extract pepsin soluble collagen from sturgeon cartilage, hydrolyze to collagen peptides and prepare SCCP nanoliposomes to explore the treatment effects of osteoarthritis in rats. ABSTRACT This study aims to extract pepsin soluble collagen (PSC) from sturgeon cartilage, hydrolyze to sturgeon cartilage collagen peptides (SCCP), and ...
Chia‐Chi Kung   +2 more
wiley   +1 more source

Relationship between corneal thickness and radius to body height [PDF]

open access: yes, 2017
Doughty, Michael   +3 more
core   +1 more source

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants

open access: yesGlobal Challenges, EarlyView.
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu   +3 more
wiley   +1 more source

Evidence of Oxidative Stress in Human Corneal Diseases

open access: bronze, 2002
Rajeev Buddi   +5 more
openalex   +1 more source

Parachlamydia acanthamoebae in domestic cats with and without corneal disease [PDF]

open access: green, 2010
Marianne Richter   +5 more
openalex   +1 more source

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

open access: yesGlia, EarlyView.
Astrocytes play an important role in glaucoma. These cells express Cx43, which can form gap junctions and hemichannels. This study shows that Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation. ABSTRACT Astrocytes in the retina and optic nerve head play an important role in the pathogenesis of ...
Khulan Batsuuri   +4 more
wiley   +1 more source

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