Results 291 to 300 of about 9,423,348 (360)

Deficiency of 2‐Oxoglutarate Carrier (Slc25a11) Drives RPE Epithelial‐to‐Mesenchymal Transition and Exacerbates Subretinal Fibrosis in Neovascular Age‐Related Macular Degeneration

open access: yesAging Cell, EarlyView.
The diagram shows that OGC deficiency leads to mitochondrial dysfunction, which activates the PI3K/AKT/Slug pathway and triggers epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial cells. This process promotes myofibroblast accumulation and subretinal fibrosis in laser‐induced CNV, contributing to the progression of AMD.
Mo Wang   +9 more
wiley   +1 more source

Drug‐Induced Periocular and Ocular Surface Disorders: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Various systemic and topical medications can induce ocular and periocular cutaneous adverse effects (AEs), ranging from mild to severe. These AEs may lead to ocular surface (OS) damage and, in some cases, life‐threatening complications. Drug‐induced ocular adverse reactions are generally classified into two primary categories: toxic reactions ...
Andrea Leonardi   +16 more
wiley   +1 more source

Two‐year changes of macular choroidal thickness in response to 0.01% atropine eye drops: Results from the myopia outcome study of atropine in children (MOSAIC) clinical trial

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate 2‐year changes in macular choroidal thickness (ChT) in children receiving 0.01% atropine eyedrops and its relationship with spherical equivalent refraction (SER) progression and axial length (AL) elongation. Methods A total of 250 myopic children aged 6–16 years (167%–0.01% atropine, 83‐placebo) were enrolled in the ...
Emmanuel Kobia‐Acquah   +3 more
wiley   +1 more source

Paradigms, Paradoxes, and Controversies on Keratoconus and Corneal Ectatic Diseases

open access: yes, 2018
Marcella Q. Salomão   +6 more
semanticscholar   +1 more source

Effects of customized corneal cross‐linking on higher‐order aberrations in progressive keratoconus and low‐grade myopia

open access: yesActa Ophthalmologica, EarlyView.
Abstract Objective To evaluate the effects of customized corneal collagen cross‐linking (CXL) on higher‐order aberrations (HOAs) in keratoconus (KC): vertical coma (VC), horizontal coma (HC), spherical aberration (SA), trefoil (TF) and astigmatism, compared with the same effects in healthy eyes undergoing CXL for low‐grade myopia.
Jad Hayek   +4 more
wiley   +1 more source

Progression and topographic subtypes of Terrien marginal degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To report long‐term outcomes and to search for immunological and genetic risk factors in Terrien marginal degeneration (TMD). Methods Retrospective, in part prospective, hospital‐based longitudinal follow‐up study of 32 eyes of 16 Finnish patients from 2012 to 2023. Median follow‐up was 7.3 years (range, 0.3–15.2).
Minna Ruutila   +8 more
wiley   +1 more source

Combined Vitrectomy and Clear Corneal Phacoemulsification in Patients with Vitreoretinal Diseases

open access: hybrid, 2015
Orhan Ates Ibrahim Kocer   +2 more
openalex   +1 more source

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