Results 81 to 90 of about 32,445 (276)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Vascular endothelial growth factor (VEGF) serological and lacrimal signaling in patients affected by vernal keratoconjunctivitis (VKC) [PDF]

, 2018
Background. Vernal keratoconjunctivitis (VKC) is a rare inflammatory disease involving the ocular surface, with seasonally exacerbated symptoms. Both type-1 and type-4 hypersensitivity reactions play a role in the development of VKC. Purpose.
Aventaggiato, Michele, Bruscolini, Alice, Duse, Marzia, IANNACCONE, ANDREA, Nebbioso, Marcella, Zicari, Anna Maria   +5 more
core   +1 more source

Systemic immunomodulatory strategies in high-risk corneal transplantation

Journal of Ophthalmic & Vision Research, 2017
The cornea is the most commonly transplanted tissue in the body. Although corneal grafts generally have high success rates, transplantation onto inflamed and vascularized host beds, or so-called high-risk corneal transplantation, has a high rate of graft
Tulio B Abud, Antonio Di Zazzo, Ahmad Kheirkhah, Reza Dana   +3 more
doaj   +1 more source

Quantifying the Pressure of Labial and Buccinator Regions Pre‐ and Post‐ Facial Nerve Reanimation

Head &Neck, EarlyView.
ABSTRACT Background Flaccid facial nerve paralysis (FFNP) impairs oral function and quality of life. Tensor fascia lata slings (TFL) are used to improve oral competence. This study used the Iowa Oral Performance Instrument (IOPI) to measure oral competence in patients with FFNP undergoing facial reanimation.
Emma Charters, Megan Lai, Caleb Heng, Briony Adshead, Virginia Ricketts, Tsu‐Hui Low   +5 more
wiley   +1 more source

Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]

, 2018
Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice, Lambiase, Alessandro, Rama, Paolo, Sacchetti, Marta   +3 more
core   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo, Shih‐Hao Huang, Ting‐Hsuan Dai, Shun‐Cheng Wu, Cheng‐Jung Ho, Cheng‐Chang Lu   +5 more
wiley   +1 more source

Smile Asymmetry and Eyelid Closure Following Temporalis Muscle Transfer for Facial Reanimation: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 53 studies and 1354 patients evaluates the outcomes of temporalis muscle transfer in facial nerve paralysis. Our results show that temporalis muscle transfer can restore smile asymmetry, oral commissure movement, and eyelid closure—findings that are translated to clinician‐rated assessments.
Amirpouyan Namavarian, Jonathan M. Chung, Saud Sunba, Hedyeh Ziai, Ahmed Bagit, Eimaan Khan, Antoine Eskander, Danny Enepekides   +7 more
wiley   +1 more source

Role of DZ2002 in reducing corneal graft rejection in rats by influencing Th17 activation via inhibition of the PI3K/AKT pathway and downregulation of TRAF1

Open Life Sciences
To investigate the mechanism of DZ2002, a reversible type III S-adenosyl-l-homocysteine hydrolase (SAHH) inhibitor, in alleviating corneal graft rejection in rats through the downregulation of TRAF1 and modulation of Th17 differentiation, so as to ...
Cao Qian, Li Yong, Zhang Yongqian, Tan Shuang, Long Junjun, Tian Ermiao, Dong Jie, Li Lan   +7 more
doaj   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

Medicinal Research Reviews, EarlyView.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo, Shinwon Kang, Jae Eun Yang, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Descemet stripping automated endothelial keratoplasty in Fuchs' corneal endothelial dystrophy: Anterior segment optical coherence tomography and in vivo confocal microscopy analysis [PDF]

, 2015
Background: To evaluate the in vivo corneal changes using in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) in patients with Fuchs' dystrophy who underwent Descemet stripping automated endothelial keratoplasty (
Busin, Massimo, Favuzza, Eleonora, Mencucci, Rita, Tartaro, Ruggero, Virgili, Gianni   +4 more
core   +1 more source