Results 131 to 140 of about 15,673 (182)

The Histopathology of Corneal Neovascularization

Archives of Ophthalmology, 1985
With the use of a previously described model of corneal neovascularization induced by thermal cautery, we examined the effects of inhibitors on both the incidence of corneal neovascularization and the degree of inflammatory cell response. Three known inhibitors of corneal neovascularization, 1% prednisolone acetate, indomethacin, and 0.3% flurbiprofen,
J B, Robin, L F, Regis-Pacheco, R L, Kash, D J, Schanzlin   +3 more
openaire   +2 more sources

Subconjunctival Bevacizumab for Corneal Neovascularization

Cornea, 2008
To describe whether subconjunctival bevacizumab decreases corneal neovascularization in patients with ocular surface inflammatory diseases.The study is a retrospective case series that includes 8 eyes of 7 patients with corneal neovascularization. Patients received 1-3 injections of 2.5 mg subconjunctival bevacizumab.
Priyanka P, Doctor, Pooja V, Bhat, C Stephen, Foster   +2 more
openaire   +2 more sources

Suppression of Corneal Neovascularization With Cyclosporine

Archives of Ophthalmology, 1992
We sought to determine if cyclosporine, which has been shown to suppress corneal allograft rejection, could also suppress corneal neovascularization induced by interleukin 2. Thirty A/J mice were treated with daily intramuscular injections of cyclosporine (25 mg/kg in olive oil) for 3 days before and 2 weeks following the intrastromal injection of 0.5 ...
R M, Lipman, R J, Epstein, R L, Hendricks   +2 more
openaire   +2 more sources

Treatments for Corneal Neovascularization: A Review

Cornea, 2011
Corneal neovascularization (CNV) may be a physiological response to various stimuli, but a chronic and persistent upregulation of neoangiogenesis can result in pathological CNV. Pathological blood vessels are immature and lack structural integrity, predisposing the cornea to lipid exudation, inflammation, and scarring.
Deepak, Gupta, Chris, Illingworth
openaire   +2 more sources

Inflammatory Corneal Neovascularization: Etiopathogenesis

Seminars in Ophthalmology, 2011
There is a delicate balance between pro-angiogenic stimuli and anti-angiogenic stimuli in the normal cornea. This balance allows the cornea to normally exist in a relatively avascular state, which is needed for optical clarity and vision. However, in the setting of inflammation, this balance may be shifted in favor of neovascularization.
John L, Clements, Reza, Dana
openaire   +2 more sources

Subconjunctival bevacizumab for corneal neovascularization

Graefe's Archive for Clinical and Experimental Ophthalmology, 2007
To report the efficacy of subconjunctival bevacizumab injection in patients with corneal neovascularization (NV).This retrospective interventional case study included two eyes of two patients with corneal NV due to aqueous-deficient dry eye with filamentary keratitis in the first case, and corneal graft failure in the second case.
Mesut, Erdurmus, Yuksel, Totan
openaire   +2 more sources

Photodynamic Therapy for Corneal Neovascularization

Cornea, 1991
We have previously described corneal neovascularization (CNV) induced by the intrastromal injection of interleukin-2 (IL-2) in inbred mice. Photodynamic therapy (PDT), administered by a deeply penetrating 630 nm fiberoptic laser, can destroy neoplasms and their associated neovascularization with some selectivity, but can damage neighboring tissues when
R J, Epstein, R L, Hendricks, D M, Harris   +2 more
openaire   +2 more sources

Photodynamic Therapy of Corneal Neovascularization with Verteporfin

Cornea, 2003
To describe the effect of photodynamic therapy (PDT) using verteporfin (Visudyne) on corneal neovascularization (CNV) in two patients.Two patients with corneal neovascularization were treated with a nonthermal laser light at 689 nm delivered 15 min after an intravenous infusion of verteporfin.
FOSSARELLO, MAURIZIO, PEIRETTI, ENRICO, ZUCCA, IGNAZIO ALBERTO, Serra, A.   +3 more
openaire   +3 more sources

Inhibition of Corneal Neovascularization with Propolis Extract

Archives of Medical Research, 2009
Neovascularization of the normally avascular cornea is seen in many pathological conditions including trauma, corneal transplantation, inflammation and eye diseases. Various growth factors and proteinases are involved in corneal neovascularization. Data supporting a causal role for vascular endothelial growth factor (VEGF) and matrix metalloproteinases
Keshavarz, Maryam, Mostafaie, Ali, Mansouri, Kamran, Shakiba, Yadollah, Motlagh, Hamid Reza Mohammadi   +4 more
openaire   +3 more sources

Novel bioactivity of NHERF1 in corneal neovascularization

Graefe's Archive for Clinical and Experimental Ophthalmology, 2012
This paper aimed to determine the involvement of Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) in experimental murine corneal neovascularization (NV), and to study the effect of NHERF1 on the biological properties of HUVEC and related mechanisms.Using loss- and gain-function, we investigated the biological effects of NHERF1 on HUVEC.
Peng, Chen, Ye, Wang, Lingling, Yang, Changyou, Li, Yao, Wang, Lixin, Xie, Yiqiang, Wang   +6 more
openaire   +2 more sources