Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension
Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira +7 more
wiley +1 more source
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez +7 more
wiley +1 more source
Correlating corneal and meibomian gland morphology with diabetes duration in T2DM <i>via</i> confocal microscopy. [PDF]
Li KJ +6 more
europepmc +1 more source
Fish Scales: A Multifunctional Biomaterial from Nature
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
The influence of ocular parameters on intraocular pressure values measured by different devices and the development of an optimized prediction model in a myopic population. [PDF]
Gan W +5 more
europepmc +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Bridging gaps in corneal ulcer management: Can photoactivated chromophore for infectious keratitis-corneal collagen cross-linking delay or replace therapeutic keratoplasty? [PDF]
Antonopoulou NI +4 more
europepmc +1 more source
Bone marrow mesenchymal stem cells (BMSCs) promote tendon injury repair by enhancing tenocyte function and regulating the FTO/m6A/ELOB axis. Mechanistically, BMSCs lead to the upregulation of FTO and m6A modification, which subsequently suppresses ELOB expression.
Zhao‐Rong Dai +2 more
wiley +1 more source
<i>Enterobacter cloacae</i> Keratitis in a Patient with Severe Dry Eye: A Rare Case Report and Review of the Literature. [PDF]
Cintas N +3 more
europepmc +1 more source
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source

