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Integrative genetic and genomic approaches to combine GWAS signals into biological pathways: application to corneal resistance factor [PDF]

Genome-wide association studies (GWAS) have successfully pinpointed numerous genetic loci and variants associated with complex traits and common diseases across the genome. However, an overwhelming proportion of these loci and variants reside in non-coding regions, complicating the identification of truly causal variants and elu- cidation of the ...
Jiang, Xinyi
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Corneal resistance factor and corneal hysteresis in a 6- to 18-year-old population

Journal of Cataract and Refractive Surgery, 2014
To determine the distribution and normal range of the corneal resistance factor (CRF) and corneal hysteresis (CH) in the 6- to 18-year age range and their relationship with biometric components.Dezful, Iran.Cross-sectional study.This study of Dezful school children used a multistage, stratified, cluster approach sampling.
Hassan, Hashemi, Ebrahim, Jafarzadehpur, Shiva, Mehravaran, Abbasali, Yekta, Hadi, Ostadimoghaddam, Reza, Norouzirad, Mehdi, Khabazkhoob   +6 more
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Corneal Hysteresis, Resistance Factor, Topography, and Pachymetry After Corneal Lamellar Flap

Journal of Refractive Surgery, 2007
Purpose: To measure prospectively the early changes in corneal hysteresis, topography, and pachymetry after the creation of a stromal flap cut without laser photoablation. Methods: A 37-year-old man was referred for a bioptic procedure
Damien, Gatinel, Slim, Chaabouni, Pierre-Alexandre, Adam, Jacques, Munck, Michel, Puech, Thanh, Hoang-Xuan   +5 more
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Corneal biomechanics study (1): Central corneal thickness versus corneal resistance factor

Acta Ophthalmologica, 2009
Abstract Purpose Study about the biomechanical characteristics of the cornea. Methods We studied 122 eyes of 61 patients (33 women and 28 men) selected prospectively and consecutively. Range of age was between 18 and 60 years. The following determinations were carried out: Corneal topography with KERATRON (Optikon), measurement with ORA (Reichert) and ...
Z VALYI, J IBANEZ, D PEREZ GARCíA, B JIMENEZ DEL RIO, JA CRISTOBAL   +4 more
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Corneal Hysteresis, Corneal Resistance Factor, and Intraocular Pressure Measurements in Eyes Implanted With a Small Aperture Corneal Inlay

Journal of Refractive Surgery, 2014
PURPOSE: To compare the postoperative corneal hysteresis (CH) and corneal resistance factor (CRF) of eyes implanted with a small aperture corneal inlay versus fellow eyes. METHODS: Medical records of patients who underwent small aperture corneal inlay (KAMRA; AcuFocus,
Alper, Agca, Ahmet, Demirok, Haci Ugur, Celik, Corina, van de Pol, Kadir Ilker, Cankaya, Nimet Burcu, Celik, Dilek, Yasa, Ihsan, Yilmaz, Omer Faruk, Yilmaz   +8 more
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Corneal Hysteresis and Corneal Resistance Factor in Keratoectasia: Findings Using the Reichert Ocular Response Analyzer

Ophthalmologica, 2008
<i>Aim:</i> To examine corneal hysteresis (CH) and corneal resistance factor (CRF) in normal and ectatic corneas. <i>Methods:</i> CH and CRF were measured using the Reichert Ocular Response Analyzer in patients with clinically diagnosed keratoconus (KC), forme fruste KC (FFKC) and normal eyes. <i>Results:</i> 21 eyes
Caitriona, Kirwan, Donal, O'Malley, Michael, O'Keefe   +2 more
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Ocular response analyser to assess hysteresis and corneal resistance factor in low tension, open angle glaucoma and ocular hypertension

Clinical & Experimental Ophthalmology, 2008
AbstractPurpose: The aim of this study is to compare the hysteresis and corneal resistance factor (CRF) in normal tension glaucoma (NTG), primary open angle glaucoma (POAG) and ocular hypertension (OHT) eyes measured by the ocular response analyser (ORA).Methods: This is a prospective, cross‐sectional and comparative clinical trial.
Sunil, Shah, Mohammad, Laiquzzaman, Sanjay, Mantry, Ian, Cunliffe   +3 more
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Characterization of virulence factors, antimicrobial resistance patterns and biofilm formation of Pseudomonas aeruginosa and Staphylococcus spp. strains isolated from corneal infection

Journal Français d'Ophtalmologie, 2018
Infectious keratitis is a serious ocular infection that can lead to severe visual impairment and blindness. Bacterial pathogens are responsible for nearly half of infectious keratitis cases. This study was performed to determine the virulence factors, antimicrobial resistance patterns, and biofilm formation ability of Pseudomonas aeruginosa and ...
H, Heidari, M, Hadadi, H, Sedigh Ebrahim-Saraie, A, Mirzaei, A, Taji, S R, Hosseini, M, Motamedifar   +6 more
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Donor characteristics and risk factors for methicillin‐resistant Staphylococcus aureus contamination in storage medium for corneal transplantation: A 10‐year retrospective study

Transplant Infectious Disease, 2019
AbstractPurposeThis study investigated the donor characteristics of methicillin‐resistant Staphylococcus aureus (MRSA) contamination in storage medium before transfer of corneas to preservation medium for corneal transplantation, in order to identify donor characteristic risk factors for MRSA contamination.MethodsThis retrospective, cross‐sectional ...
Yuichi Okumura, Takenori Inomata, Shizuka Miyamoto, Satoru Nakatani, Yoshimune Hiratsuka, Masahiro Yamaguchi, Satoshi Iwamoto, Akira Murakami   +7 more
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[The influence of corneal hysteresis and corneal resistance factor on the measurement of intraocular pressure].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2007
The influence of central corneal thickness (CCT) on the measurement of intraocular pressure (IOP) has been discussed extensively in recent years. The problem, however, has not been solved so far. In addition to CCT there are probably further biomechanical properties that play a role in IOP measurement. We wanted to find out whether these properties are
A, Hager, B, Schroeder, M, Sadeghi, M, Grossherr, W, Wiegand   +4 more
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