Results 251 to 260 of about 361,834 (295)

Familial Corneal Scarring: A New Dystrophy?

Ophthalmology, 1984
A 34-year-old white man with skin manifestations of the epidermal nevus syndrome was found to have anesthetic corneas, dry eyes, and localized opaque nodular elevations of both corneas. Similar corneal lesions, unassociated with corneal anesthesia, were found in four family members.
L W, Hirst, E R, Farmer, W R, Green, A, Silver, F B, Walsh   +4 more
openaire   +2 more sources

An injectable thermoresponsive-hydrogel for lamellar keratoplasty: In-situ releases celastrol and hampers corneal scars.

Journal of Controlled Release
Corneal stromal fibrosis is a common cause of visual impairment resulting from corneal injury, inflammation and surgery. Therefore, there is an unmet need for inhibiting corneal stromal fibrosis.
Zhanrong Li, Ruixing Liu, Xiacong Zhang, Zhihua Guo, Xin Geng, D. Chu, Haohao Cui, A. Zhang, Wen Li, Lei Zhu, Jingguo Li   +10 more
semanticscholar   +1 more source

Changing Trends in Penetrating Keratoplasty Indications between 2011 and 2018 – Histopathology of 2123 Corneal Buttons in a Single Center in Germany

Current Eye Research, 2020
Purpose: To analyse the changing trends in penetrating keratoplasty indications between January 2011 and December 2018, at the Department of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany.
M. T. Pluzsik, B. Seitz, F. Flockerzi, A. Langenbucher, Gábor Tóth, R. Bohle, N. Szentmáry   +6 more
semanticscholar   +1 more source

A Corneal Scarring Model

2013
Corneal opacification (i.e., haze) following a non-denaturing acute injury to the cornea is a process which takes about 5 days to manifest itself, indicating that it is the consequence of cellular and molecular biological processes. In order to obtain a better understanding of the haze development process, and to test candidate anti-haze therapies, we ...
Daniel J, Gibson, Gregory S, Schultz
openaire   +2 more sources

Mouse Models of Corneal Scarring

2017
Corneal scarring is an obligatory consequence of stroma corneal injury and is a major cause of decreased visual quality and vision loss worldwide. There are currently no satisfactory intervention therapies for corneal fibrosis. In this chapter, we describe well-established in vivo corneal wound models to allow researchers to investigate epithelial and ...
Laure, Rittié, Audrey E K, Hutcheon, James D, Zieske   +2 more
openaire   +2 more sources

Muse cell spheroids have therapeutic effect on corneal scarring wound in mice and tree shrews

Science Translational Medicine, 2020
Corneal stromal cells differentiated from Muse spheroids had therapeutic effects on wounded corneas in mice and tree shrews. aMUSEment in sight Scars from corneal injuries are a major cause of blindness.
Yonglong Guo, Yunxia Xue, Peiyuan Wang, Zekai Cui, Jixing Cao, Shiwei Liu, Quan Yu, Qiaolang Zeng, Deliang Zhu, Mengyuan Xie, Jun Zhang, Zhijie Li, Hongwei Liu, Jingxiang Zhong, Jiansu Chen   +14 more
semanticscholar   +1 more source

Increased Corneal Scarring after Phototherapeutic Keratectomy in Fuchs' Corneal Dystrophy

Journal of Refractive Surgery, 1997
ABSTRACT PURPOSE: A 63-year-old female with Fuchs' endothelial corneal dystrophy, stromal edema and subepithelial scarring was inappropriately treated with phototherapeutic keratectomy, leading to a central focal circular corneal scar and decreased visual acuity that required penetrating keratoplasty. METHOD: The host corneal button
M, Alaa, G O, Waring, A, Malaty, H, Grossniklaus   +3 more
openaire   +2 more sources

Deep Corneal Scarring in Pellucid Marginal Corneal Degeneration

Cornea, 1992
Crescent-shaped, deep corneal scars were observed in seven (39%) of 18 patients with pellucid marginal corneal degeneration. The scars most likely represent a degenerative change related to the precipitous alteration in curvature of the cornea in that area.
openaire   +2 more sources

Effect of herpes simplex keratitis scar location on bilateral corneal nerve alterations: an in vivo confocal microscopy study

British Journal of Ophthalmology, 2020
Aims To evaluate the impact of herpes simplex virus (HSV)-induced scar location on bilateral corneal nerve alterations using laser in vivo confocal microscopy (IVCM).
Chareenun Chirapapaisan, Rodrigo T. Muller, A. Şahin, A. Cruzat, B. Cavalcanti, A. Jamali, D. Pavan-Langston, P. Hamrah   +7 more
semanticscholar   +1 more source

Ichthyosis and Corneal Scarring

Archives of Ophthalmology, 2011
terns and apparent oblique muscle overaction. Arch Ophthalmol. 2010;128(6):712-718. 31. Spielmann A. The “oblique Kestenbaum” procedure revisited. In: Lenk-Schafer M, ed. Transactions International Orthoptic Congress, Harrogate, UK. Harrogate, UK: Orthoptic Horizons; 1987. 32. Kushner B. Grand rounds #1. Binocul Vis. 1985;1: 35-38. 33.
openaire   +1 more source