Results 41 to 50 of about 124,546 (237)

Indications and surgical techniques for corneal transplantation at a tertiary referral center

open access: yesJournal of Ophthalmic & Vision Research, 2019
Purpose: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. Methods: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran ...
Hossein Jamali, Ahmad Reza Gholampour
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

The Significance of Scars: Patient and Clinician Perspectives [PDF]

open access: yes, 2019
The formation of a scar represents the extension of regenerative wound repair mechanisms. On the one hand, scar tissue helps in wound closure by supporting wound contracture and reepithelization.
Karadağ, Ayşe Serap, Özlü, Emin
core   +2 more sources

Molecular and Cellular Mechanisms of Corneal Scarring and Advances in Therapy

open access: yesInternational Journal of Molecular Sciences, 2023
On the basis of WHO global blindness data, it may be stated that 23 million people globally suffer from unilateral corneal blindness, while 4 [...]
Matthias Fuest   +2 more
openaire   +3 more sources

Evaluation of interface quality in organ-cultured lamellar corneal transplants [PDF]

open access: yes, 2012
Background: With increasing numbers of lamellar keratoplasties, eye banks are challenged to deliver precut lamellar donor tissue. In Europe, the most common technique of corneal storage is organ culture which requires a deswelling process before surgical
Kohnen, Thomas   +7 more
core   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

open access: yesVIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore   +5 more
wiley   +1 more source

Diagnostic Utility of Full‐Length BP180 and Native BP180‐α6β4 Integrin Complex ELISAs in Serologically Inconclusive Mucous Membrane Pemphigoid

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Mucous membrane pemphigoid (MMP) is a chronic autoimmune subepithelial blistering disorder of mucosal surfaces that can cause irreversible scarring, blindness, or dysphagia. Early diagnosis is challenging because histopathology is nonspecific and conventional BP180 NC16A ELISAs have limited sensitivity.
Yukiko Ishizuka   +10 more
wiley   +1 more source

Recent developments in retinal lasers and delivery systems

open access: yesIndian Journal of Ophthalmology, 2014
Photocoagulation is the standard of care for several ocular disorders and in particular retinal conditions. Technology has offered us newer lasing mediums, wavelengths and delivery systems.
Naresh Kumar Yadav   +3 more
doaj   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki   +10 more
wiley   +1 more source

2-ethylpyridine, a cigarette smoke component, causes mitochondrial damage in human retinal pigment epithelial cells in vitro

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: Our goal was to identify the cellular and molecular effects of 2-ethylpyridine (2-EP, a component of cigarette smoke) on human retinal pigment epithelial cells (ARPE-19) in vitro.
S Mansoor   +4 more
doaj   +1 more source

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