Results 101 to 110 of about 36,125 (294)

Corneal thickness and elevation measurements using swept‐source optical coherence tomography and slit scanning topography in normal and keratoconic eyes

, 2013
Background: To compare corneal thickness and corneal elevation using swept source optical coherence tomography and slit scanning topography. Design: Prospective study. Participants: 41 normal and 46 keratoconus subjects.
Leung, Christopher K.S., Vishal Jhanji, Christopher KS Leung, Ye, Cong, Bingzhi Yang, Yu, Marco, Marco Yu, Yang, Bingzhi, Jhanji, Vishal, Cong Ye   +9 more
core   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Corneal Microlayer Optical Tomography Review

, 2019
La technologie d'imagerie à très haute résolution du segment antérieur (UHR-OCT) utilise une résolution de 1 à 4 μm pour fournir une imagerie non invasive du film lacrymal et de la cornée. Cette nouvelle technologie d'imagerie à haute définition améliore notre compréhension de la structure normale et des changements pathologiques de la cornée, et la ...
Vatookarn Roongpoovapatr, Jane C. Cook, Taher K. Eleiwa, Sonia H. Yoo, Mohamed Abou Shousha   +4 more
openaire   +2 more sources

Agreement of post-LASIK corneal power and corneal thickness measurements by pentacam and GALILEI corneal tomography systems

Journal of the Chinese Medical Association, 2019
Post-LASIK corneal conditions cannot be accurately measured by traditional optometric approaches. Therefore, we aimed to analyze the agreement of two rotating Scheimpflug cameras in corneal assessment.Fifty otherwise healthy volunteers who had undergone LASIK were recruited in this study.
Yun-Hsiu, Hsieh, Tzu-Heng, Weng, Yu-Ching, Chou, Kuan-Liang, Wu, Chang-Min, Liang, Ming-Cheng, Tai   +5 more
openaire   +2 more sources

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Donor disc attachment assessment with intraoperative spectral optical coherence tomography during descemet stripping automated endothelial keratoplasty

Indian Journal of Ophthalmology, 2013
Optical coherence tomography has already been proven to be useful for pre- and post-surgical anterior eye segment assessment, especially in lamellar keratoplasty procedures.
Edward Wylegala, Anna K Nowinska, Ewa Wroblewska-Czajka, Dominika Janiszewska   +3 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Applications of Imaging Technologies in Fuchs Endothelial Corneal Dystrophy: A Narrative Literature Review

Bioengineering
Fuchs endothelial corneal dystrophy (FECD) is a complex genetic disorder characterized by the slow and progressive degeneration of corneal endothelial cells.
Sang Beom Han, Yu-Chi Liu, Chang Liu, Jodhbir S. Mehta   +3 more
doaj   +1 more source

Comparison of endothelial/Descemet’s membrane complex thickness with endothelial cell density for the diagnosis of corneal transplant rejection

Therapeutic Advances in Ophthalmology, 2018
Purpose: This study compared the effectiveness of endothelial/Descemet’s membrane complex thickness obtained using high-definition anterior segment optical coherence tomography with endothelial cell density obtained using confocal microscopy as ...
Christopher Smith, Daniel Kaitis, Jordan Winegar, Sean Edelstein, Matthew Council, George Kontadakis, Rocio Bentivegna, Mohamed Abou Shousha   +7 more
doaj   +1 more source

Clinical features and visual function in a patient with Fish-eye disease: Quantitative measurements and optical coherence tomography

American Journal of Ophthalmology Case Reports, 2018
Purpose: We describe a case of fish-eye disease (FED) where the clinical features and visual function were investigated using anterior segment optical coherence tomography (OCT) and quantitative measurements.
Masanori Kanai, Shizuka Koh, Daisaku Masuda, Masahiro Koseki, Kohji Nishida   +4 more
doaj   +1 more source