SIRT1 Prevents Lens Epithelial Cell Senescence During Age‐Related Cataract via Regulating p66Shc
Schematic illustration of NMN‐mediated alleviation of age‐related cataract via SIRT1/p66Shc pathway–dependent inhibition of mitochondrial dysfunction and LEC senescence. ABSTRACT Lens epithelial cell (LEC) senescence is one of the key pathological processes of age‐related cataract (ARC) and is associated with oxidative stress, mitochondrial dysfunction,
Huirui Liu+8 more
wiley +1 more source
BackgroundThe study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region.MethodsThe clinical records of 359 patients (394 eyes) who underwent corneal ...
Chunxiao Yan+12 more
doaj +1 more source
The Role of Scalp EEG Recordings During Cortical Visual Prosthesis Testing
This article describes the role of recording scalp EEG for projects that are developing cortical visual prosthesis systems. It concludes that EEG is not required during basic threshold and spatial mapping studies, but should be considered when higher levels of stimulation and video‐camera stimulation are employed.
Katarina Stephan+13 more
wiley +1 more source
Perceptions and Struggle of Corneal Donation and Transplants: You can see the World even after Death
Objective: To assess knowledge, opinion and perception of the general population regarding corneal donation and transplantation. Another objective was to investigate desires, fulfilment, battle and results of patient’s experiences of Corneal Transplant ...
Sana Abbas, Aisha Rafique
doaj +2 more sources
Fuchs endothelial corneal dystrophy (FECD) is the most common indication for corneal transplantation in the United States. Recently, descemetorhexis without endothelial keratoplasty (DWEK) or Descemet’s stripping only (DSO) has become an attractive ...
Pimpiroon Ploysangam, Sangita P. Patel
doaj +1 more source
Limbal Stem Cells and Corneal Epithelial Regeneration: Current Status and Prospectives [PDF]
The clear cornea functions like a window that controls the entry of light for visual information and plays a protective role. The failure of appropriate repair following corneal injury results in loss of corneal function.
He, J+4 more
core
Human Bone Derived Collagen for the Development of an Artificial Corneal Endothelial Graft. In Vivo Results in a Rabbit Model [PDF]
This work was supported by Fundación Mutua Madrileña, Government of Asturias (FEDER-EU - FC-15-GRUPIN 14-141) and ...
Alfonso Sánchez, José Fernando+9 more
core +2 more sources
Progression and topographic subtypes of Terrien marginal degeneration
Abstract Purpose To report long‐term outcomes and to search for immunological and genetic risk factors in Terrien marginal degeneration (TMD). Methods Retrospective, in part prospective, hospital‐based longitudinal follow‐up study of 32 eyes of 16 Finnish patients from 2012 to 2023. Median follow‐up was 7.3 years (range, 0.3–15.2).
Minna Ruutila+8 more
wiley +1 more source
Potential Role of Induced Pluripotent Stem Cells (IPSCs) for Cell-Based Therapy of the Ocular Surface [PDF]
The integrity and normal function of the corneal epithelium are crucial for maintaining the cornea's transparency and vision. The existence of a cell population with progenitor characteristics in the limbus maintains a dynamic of constant epithelial ...
Casaroli Marano, Ricardo Pedro+4 more
core +3 more sources
Transplantation of cultured bovine corneal endothelial cells to rabbit cornea: clinical implications for human studies. [PDF]
Denis Gospodarowicz+2 more
openalex +1 more source