Results 141 to 150 of about 1,194,426 (349)

PD‐L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC‐RPE Grafts in Retinal Degeneration

Cell Proliferation, EarlyView.
We generated immune‐tolerant mature hESC‐RPE cells by overexpressing PD‐L1. PD‐L1‐expressing hESC‐RPE grafts exhibited significantly higher survival, reduced apoptosis and enhanced visual protection in retinal degeneration models, which presents an alternative target to improve the efficiency of hESC‐RPE‐based therapy for AMD. ABSTRACT Immune rejection
Bowen Li, Xue Zhang, Yajie Fang, Min Chen, Qiyou Li, Yuxiao Zeng, Chunge Ren, Chengang Wang, Yingxue Lv, Jia Lu, Hongling Liu, Yong Liu   +11 more
wiley   +1 more source

Ellagic Acid‐Loaded sEVs Encapsulated in GelMA Hydrogel Accelerate Diabetic Wound Healing by Activating EGFR on Skin Repair Cells

Cell Proliferation, EarlyView.
Ellagic acid (EA) was loaded in small extracellular vehicles (sEVs) derived from chorionic plate‐mesenchymal stem cells (CP‐MSCs) and then encapsulated in GelMA to construct Gel‐EA‐sEVs, which can be a promising treatment approach for diabetic wounds by improving biological functions of skin repair cells.
Lige Tian, Zihao Wang, Shengqiu Chen, Kailu Guo, Yaying Hao, Liqian Ma, Kui Ma, Junli Chen, Xi Liu, Linlin Li, Xiaobing Fu, Cuiping Zhang   +11 more
wiley   +1 more source

A murine model of interlamellar corneal transplantation [PDF]

, 1998
Carmen Lau, Susan M. Nicholls, D L Easty
openalex   +1 more source

Causes of congenital corneal opacities and their management in a tertiary care center. [PDF]

, 2020
PURPOSE: To evaluate causes and management of congenital corneal opacities (CCO) diagnosed in a tertiary care eye center and to compare the data with a previous study at the same institution.
Hammersmith, Kristin M, Karadag, Remzi, Nagra, Parveen K, Rapuano, Christopher J   +3 more
core   +1 more source

Dental and Maxillofacial Trauma Skills Content in the Southeast Asian Dental Curricula: A Mixed Methods Study

Dental Traumatology, EarlyView.
ABSTRACT Background/Aim This study aims to review contents related to dental maxillofacial trauma (DMT) in the dental curricula of Southeast Asian (SEA) countries and assess their effectiveness in equipping future dental professionals with the necessary skills for the efficient management of DMT.
Rodrigo Mariño, Nabihah Dziaruddin, Kathreena Kadir, Christina P. C. Sim, Bernadette Quah, Papimon Chompu‐inwai, Varisara Sirimaharaj   +6 more
wiley   +1 more source

Corneal epithelial stem-cell transplantation [PDF]

, 1997
Michele De Luca, Graziella Pellegrini
openalex   +1 more source

Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof‐of‐concept clinical study

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects >25 million people worldwide and is often associated with neuroinflammation. Increasing evidence links deficiency or malfunctioning of the enzyme phosphoglycerate dehydrogenase (PHGDH), which converts 3‐phosphoglycerate to generate serine and the neurotransmitter glycine, with (drug‐resistant ...
Karin Thevissen, Annelii Ny, Daniëlle Copmans, Jana Tits, Kenichi Kamata, Eva Gielis, Kevin Longin, Jo Sourbron, Peravina Thergarajan, Tracie Huey‐Lin Tan, Idrish Ali, Nigel C. Jones, Terence J. O'Brien, Mastura Monif, Bridgette D. Semple, Christine Germeys, Benedetta Frizzi, Virginia Minniti, Sebastian Perrone, Carole L. Linster, Ilaria Elia, Ludo Van Den Bosch, Bruno P. A. Cammue, Arnout Voet, Lieven Lagae, Peter de Witte   +25 more
wiley   +1 more source

Severe bilateral descemetoceles in Alpha-1 antitrypsin deficiency. [PDF]

, 2019
PurposeTo report a case of severe bilateral descemetoceles in a patient with alpha-1 antitrypsin (A1AT) deficiency during intensive care unit hospitalization.ObservationsA 42-year-old male presented with sub-acute bilateral vision loss during an ...
Baqai, Jeanine, Ma, Jeffrey
core   +1 more source

Emerging roles for integrated stress response signaling in homeostasis

The FEBS Journal, EarlyView.
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar, Lydia Grmai, Deepika Vasudevan   +2 more
wiley   +1 more source

Knowledge, Attitudes and Practices of Intensive Care Nurses Regarding Eye Care

Journal of Clinical Nursing, EarlyView.
ABSTRACT Introduction Care for patients in the intensive care unit (ICU) must support all body systems. However, ICU nurses often focus on life‐threatening conditions, giving less attention to other critical areas such as eye care. Objective This study aims to determine ICU nurses' knowledge, attitudes and practices regarding eye care.
Serap Gungor, Senem Andı, Sumeyye Akçoban, Betul Tosun   +3 more
wiley   +1 more source