Results 261 to 270 of about 24,848 (319)

Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal

open access: yesClinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder characterized by anhidrosis, self‐mutilation, and insensitivity to pain and temperature. While genetic testing confirms the diagnosis, it is not always feasible, making clinical recognition crucial in resource‐limited settings.
Sobin Pant   +4 more
wiley   +1 more source

Utilizing Cordyceps cicadae Mycelium as a Potential Supplement for Alleviating UVB‐Induced Photokeratitis Symptoms In Vivo

open access: yeseFood, Volume 6, Issue 4, August 2025.
Cordyceps cicadae mycelium extracts (CCME) have been reported to exert beneficial effects on ocular diseases. TV, TBUT, and cornea surface indexes were improved with oral CCME intake. Immunohistochemical assays showed that p63 + , PCNA, NF‐κB and COX‐2 expressions decreased in the CCME group than that of the UVB group. The corneas of those treated with
Tsung‐Han Lu   +6 more
wiley   +1 more source

Genistein in the Prevention and Treatment of Periodontitis: A Review

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Genistein, an isoflavone compound with diverse pharmacological activities, shows potential as an adjunctive therapeutic agent for periodontitis due to its anti‐inflammatory, antioxidant, and osteoprotective properties. Genistein not only mitigates the degradation of periodontal soft tissue but also demonstrates a protective effect on alveolar bone by ...
Yujun Lu   +6 more
wiley   +1 more source

Elucidation of the Hemostatic and Anti‐Inflammatory Effects of Walnut Shell Ethanol Extract by Network Pharmacology and Experimental Verification

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Forty‐five components of WSEE were identified by UPLC‐Q‐TOF‐MS. The main targets of WSEE were PTPN2, ADRB2, LTA4H, and so on in wound healing. WSEE has an anti‐inflammatory effect in LPS‐stimulated RAW264.7 cells, procoagulant activity in vitro, and shortens hemostasis time in vivo.
Ying He   +9 more
wiley   +1 more source

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

open access: yesJournal of Applied Toxicology, Volume 45, Issue 8, Page 1417-1425, August 2025.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens   +3 more
wiley   +1 more source

Sociodemographic and Clinical Predictors of Prolonged Length of Corneal Ulcer Hospitalizations.

open access: yesJAMA Ophthalmol
Akosman S   +5 more
europepmc   +1 more source

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