Results 51 to 60 of about 29,016 (334)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Geometric, Environmental and Hardware Error Sources of a Ground-Based Interferometric Real-Aperture FMCW Radar System

open access: yesRemote Sensing, 2018
Ground-based interferometric radar systems have numerous environmental monitoring applications in geoscience. Development of a relatively simple ground-based interferometric real-aperture FMCW radar (GB-InRAR) system that can be readily deployed in field
Rune Gundersen   +2 more
doaj   +1 more source

Multiple pass reimaging optical system [PDF]

open access: yes, 1973
An optical imaging system for enabling nonabsorbed light imaged onto a photodetective surface to be collected and reimaged one or more times onto that surface in register with the original image. The system includes an objective lens, one or more imaging
Brown, R. M., Gunter, W. D., Jr.
core   +1 more source

Investigation of ducts as a “radar pinhole” for detecting objects through a wall [PDF]

open access: yes, 2016
There is a continuing interest in the through-the-wall capabilities of radar. It has been found that walls behave as a low-pass medium, and therefore through-the-wall radar has been restricted to frequencies in the low GHz range.
Whitelonis, Nicholas John
core   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Enhancement of ECE SuperPin Curved Reflex Reflector by the Use of Double Pins with Corner Cubes

open access: yesApplied Sciences, 2019
A new, highly efficient curved reflex reflector is proposed to meet the requirement of EU ECE (Economic Commission for Europe) regulations based on the commercial design provided by an automotive company which has been in mass production.
Lanh-Thanh Le   +6 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Home - About - Disclaimer - Privacy