Results 241 to 250 of about 1,004,947 (332)
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source
Reply to Comment on "Identification of Negative Ion at <i>m/z</i> 20 Produced by Atmospheric Pressure Corona Discharge Ionization under Ambient Air". [PDF]
Takayama M.
europepmc +1 more source
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang +17 more
wiley +1 more source
Protein corona formed on lipid nanoparticles compromises delivery efficiency of mRNA cargo. [PDF]
Voke E +10 more
europepmc +1 more source
Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan +17 more
wiley +1 more source
Terminal sialic acids in the nanoparticle corona modulate cellular uptake. [PDF]
Dobricic M +9 more
europepmc +1 more source
This study addresses the core scientific question of atomic‐scale structural units and their assembly mechanisms by integrating ion implantation technology— originally developed in nuclear physics research—with flexible intelligent polymers. Through this interdisciplinary approach, we have enabled on‐demand customization of surface functionalities and ...
Yi Chen +11 more
wiley +1 more source
Region-dependent mechanical parameters in simulating cerebral atrophy. [PDF]
Tueni N +4 more
europepmc +1 more source

