Results 51 to 60 of about 1,004,947 (332)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Spectral analysis of 3D MHD models of coronal structures
, 2009 We study extreme-ultraviolet emission line spectra derived from three-dimensional magnetohydrodynamic models of structures in the corona. In order to investigate the effects of increased magnetic activity at photospheric levels in a numerical experiment,
Barnes +25 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The protein corona affects the clinical applications, organ targeting, and safety assessment of nanomaterials, and prediction of the protein corona would be valuable for the design of ideal nanomaterials.
Zhan Ban +5 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Online Learning to Prevent the Spread of Pandemic Corona Virus in Indonesia
, 2020 In March 2020 almost all cities in Indonesia face the scary viruses namely corona. The speed of the viruses spread influences all aspects of life without exception. Education system is one of the crucial things which is influenced by this virus.
Henny Yulia
semanticscholar +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
, 2009 We propose a new model for explaining the observations of more than mass proportional heating of heavy ions in the polar solar corona. We point out that a large number of small scale intermittent shock waves can be present in the solar corona.
Zimbardo, Gaetano
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Expression of NKG2A inhibitory receptor on cytotoxic lymphocytes as an indicator of severity in Corona Virus Disease 2019 (COVID-19) patients [PDF]
, 2021 Marwa Yasin +3 more
openalex +1 more source