Results 51 to 60 of about 302,916 (292)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Strengthening local capacity for mathematical modelling in low- and middle-income countries: the process and lessons learnt in implementing the first cohort of Nigeria malaria modelling fellowships

Malaria Journal
Background Mathematical modelling plays a crucial role in understanding malaria epidemiology and evaluating anti-malarial interventions. In sub-Saharan Africa, National Malaria Control Programs are increasingly collaborating with modellers to optimize ...
Chijioke Kaduru, Uche Ibe, Shina Aladeshawe, Adaeze Eche-George, Ganiyat Eshikhena, Dumale Aadum, Bassey Okon, Emmanuel D. Iorkase, Kesiye Leghemo, Oladipo Ogunbode, Chukwu Okoronkwo, Onyebuchi Okoro, Ehimario U. Igumbor, Abisoye Oyeyemi, Perpetua Uhomoibhi, Seye Babatunde   +15 more
doaj   +1 more source

A new approach to the maser emission in the solar corona [PDF]

, 2015
Aims. The electron plasma frequency ωpe and electron gyrofrequency Ωe are two parameters that allow us to describe the properties of a plasma and to constrain the physical phenomena at play, for instance, whether a maser instability develops.
Regnier, Stephane, S. Régnier
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

The impact of strengthened ward development committees on utilisation of reproductive maternal and child health services in Bayelsa State, Nigeria

BMC Public Health
Introduction Maternal and Child Health (MCH) conditions continue to be a major public health concern in low- and middle-income countries (LMICs), which account for 94% of maternal deaths worldwide.
Chijioke Kaduru, Ganiyat Eshikhena, Eghe Abe, Nwadiuto Ojielo, Neni Aworabhi, Happiness Masa, Uche Ibe, Timiebiere Sabenus, Godwin Idim, Geraldine Mbagwu, Ojonimi Alfred, Paul Abiodun, Pabara Igwele, Abisoye Oyeyemi   +13 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

A qualitative study of health worker experiences navigating dual financing streams of statutory and project-based funding in Nigerian primary health centres

Discover Public Health
Background Nigeria’s Basic Health Care Provision Fund (BHCPF) and project-based Direct Facility Financing (DFF) often operate concurrently in primary health care facilities.
Olamide Akeboi, David Bassey, Marvellous Oni, Aderonke Sule-Odu, Oluwaseun Oladoye, Godwin Idim, Obiageli Onwusaka, Michael Oguntoye, Osoko Oluyemi, Muideen Olatunji, Nnenna Oji, Ifeoma Ezenyi, Dupsy Akoma, Fayokemi Olususi, Abisoye Oyeyemi, Nusirat Elelu, Oluwole Odutolu, Chijioke Kaduru   +17 more
doaj   +1 more source

Prevalence of airflow obstruction according GOLD, ATS and ERS criteria in symptomatic ever-smokers referring to a Pulmonary Rehabilitation Department

Monaldi Archives for Chest Disease, 2015
Aim. To evaluate in a Pulmonary Rehabilitation (PR) setting the prevalence of airflow obstruction (AO) in either current or former smokers ≥45 years old both with dyspnoea and with chronic productive cough, using European Respiratory society (ERS ...
N. Barbarito, A. Vaghi, E. De Mattia
doaj   +1 more source