Results 201 to 210 of about 38,591 (254)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

Online anatomical images are an effective resource to improve knowledge acquisition and practical exam performance in gross anatomy

open access: yesAnatomical Sciences Education, Volume 19, Issue 8, Page 1269-1278, August 2026.
The use of cadaveric images in visceral anatomy is associated with improved knowledge acquisition, higher motivation and satisfaction. Besides, the use of anatomical images significantly improved students' practical exam performance in the dissection room.
Amparo Gimeno   +4 more
wiley   +1 more source

National Trends & Disparities in Ischemic Heart Disease & Cardiac Arrhythmias Related Mortality in the United States From 1999 to 2024: A CDC Wonder Analysis

open access: yesClinical Cardiology, Volume 49, Issue 8, August 2026.
This graphical abstract summarizes long‐term national trends and demographic disparities in mortality related to co‐occurring ischemic heart disease (IHD) and cardiac arrhythmias in the United States between 1999 and 2024, derived from the Centers for Disease Control and Prevention Wide‐ranging Online Data for Epidemiologic Research (CDC WONDER ...
Muhammad Murtaza   +10 more
wiley   +1 more source

Temporal Trends in Mortality Due to Ischemic Heart Disease and Cardiac Arrhythmias in the United States From 1999 to 2023

open access: yesClinical Cardiology, Volume 49, Issue 8, August 2026.
Mortality involving ischemic heart disease and cardiac arrhythmias declined over two decades before rising sharply during the COVID‐19 pandemic. Significant disparities by sex, race, region, and rurality emphasize the need for equitable cardiovascular prevention and management. ABSTRACT Background Ischemic heart disease (IHD) remains a leading cause of
Taha Alam   +13 more
wiley   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal   +2 more
wiley   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba   +2 more
wiley   +1 more source

Conspiracy Theory Endorsement Profiles: A Cluster Validation Study

open access: yesEuropean Journal of Social Psychology, Volume 56, Issue 5, Page 861-872, August 2026.
ABSTRACT A substantial body of research has investigated the determinants of conspiratorial beliefs, yet little is known about different conspiracy theory endorsement profiles. The present study used cluster analysis on a set of 52 conspiratorial statements tapping into six conspiracy theory types to identify and validate conspiracy theory endorsement ...
Otto Mäki   +6 more
wiley   +1 more source

Coronavirus disease 2019 infection reduces EGFR‐TKI efficacy in non‐small cell lung carcinoma: Real‐world evidence from a multicenter propensity‐matched cohort

open access: yesInternational Journal of Cancer, Volume 159, Issue 3, Page 699-708, 1 August 2026.
What's New? Lung cancer patients with COVID‐19 experience significantly increased risk for severe illness and mortality. However, research addressing the effect of COVID‐19 on non‐small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) remains unknown.
Wenjie Tang   +13 more
wiley   +1 more source

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