Results 161 to 170 of about 280,119 (256)

A Static Phantom for Harmonization of Hyperpolarized [1–13C]Pyruvate Metabolic Magnetic Resonance Imaging

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1769-1777, October 2026.
ABSTRACT PurposeTo develop and characterize a static, reusable 13C phantom designed to assess and support the harmonization of MRI setups used for hyperpolarized (HP) [1‐13C]pyruvate imaging. MethodsThe phantom was designed as a 200‐mm‐diameter polycarbonate sphere filled with 8M natural abundance urea and incorporating distinct modules for assessing ...
Kristina P. Jacobsen   +3 more
wiley   +1 more source

The Fiery Eyes of a Maenad: Origin Determination of Faceted Garnet Eye Inlays in a Roman Bronze Bust From Southern Tyrol

open access: yesArchaeometry, Volume 68, Issue 5, Page 898-907, October 2026.
ABSTRACT In 1837, the Tyrolean State Museum Ferdinandeum in Innsbruck, Austria, purchased a Roman bronze statue of a maenad from the 2nd century ce with red garnets as facetted eye inlays found near Brixen, Southern Tyrol. These garnets were investigated using optical microscopy, a portable hand‐held and a stationary micro‐X‐ray fluorescence device, as
H. Albert Gilg   +3 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

CORONAL HOLES AND THE HIGH-SPEED SOLAR WIND

open access: yes, 2008
. Coronal holes are the lowest density plasma components of the Sun’s outer atmosphere, and are associated with rapidly expanding magnetic fields and the acceleration of the high-speed solar wind.
Steven R. Cranmer
core  

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao   +11 more
wiley   +1 more source

Catheter Thrombectomy of Massive Pulmonary Embolism Secondary to Spongostan Embolisation: A Case Report

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 1029-1033, September 1, 2026.
ABSTRACT Novel adjuvant hemostatic agents are increasingly used in surgical procedures to achieve hemostasis. We present a case of embolisation of hemostatic agents during a neurosurgical operation, causing massive PE requiring venoarterial extracorporeal membrane oxygenation support, in a 7‐year‐old boy.
Talya Finke   +3 more
wiley   +1 more source

Left Cerebellar‐Right Frontal Uncoupling in Female First‐Episode Major Depressive Disorder: Synaptic Evidence From [18F]UCB‐H PET

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This study investigates cerebello‐cerebral synaptic function in female first‐episode major depressive disorder (FMD) using [18F]UCB‐H PET imaging. Compared to healthy controls (HCs), FMD patients show reduced SUVR in the left cerebellar lobule VII and synaptic tracer uptake in the left cerebellar lobule VIII, which correlates negatively with depression
Juehan Wang   +6 more
wiley   +1 more source

Oligodendrocyte‐Targeted SGK1.1 Inhibition Alleviates White Matter Injury and Cognitive Impairment in Alzheimer's Disease via Modulation of HDAC2 Phosphorylation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
We found an early Sgk1.1 mRNA upregulation within oligodendrocyte‐lineage cells of 5 × FAD mice, implicating SGK1.1 signaling as an early driver of myelin pathology. Mechanistically, SGK1.1 promotes HDAC2 phosphorylation at S422/S424, thereby impairing oligodendrocyte maturation.
Shiji Deng   +13 more
wiley   +1 more source

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