Results 61 to 70 of about 280,119 (256)

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

The spatial relationship between active regions and coronal holes and the occurrence of intense geomagnetic storms throughout the solar activity cycle [PDF]

Annales Geophysicae, 1998
We study the annual frequency of occurrence of intense geomagnetic storms (Dst < –100 nT) throughout the solar activity cycle for the last three cycles and find that it shows different structures.
S. Bravo, J. A. L. Cruz-Abeyro, D. Rojas
doaj   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Deep Brain Stimulation Reduces Conflict‐Related Theta and Error‐Related Negativity in Patients With Obsessive–Compulsive Disorder

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Obsessive–compulsive disorder (OCD) is a psychiatric disorder with alterations of cortico‐striato‐thalamo‐cortical loops and impaired performance monitoring. Electrophysiological markers such as conflict‐related medial frontal theta (MFT) and error‐related negativity (ERN) may be altered by clinically effective deep brain ...
Elena Sildatke, Theo O. J. Gruendler, Markus Ullsperger, Till A. Dembek, Juan Carlos Baldermann, Sina Kohl, Veerle Visser‐Vandewalle, Daniel Huys, Jens Kuhn, Thomas Schüller   +9 more
wiley   +1 more source

Arthroscopic Iliac Crest Bone Grafting for Shoulder Glenoid Defect Augmentation Using a "Three-Pulley Four-Point Antirotation" Suture Anchor Technique. [PDF]

Arthrosc Tech
Abstract Treatment options for severe glenoid bone defects caused by recurrent anterior shoulder instability include autologous coracoid transfer and bone graft reconstruction. The effect of bone‐grafting techniques is satisfactory, and the fixation methods for the bone block include screws or suture buttons.
Gong L, Hou H, Zhou W, Fan S, Hu L, Zhou M.   +5 more
europepmc   +2 more sources

The impact of coronal hole characteristics and solar cycle activity in reconstructing coronal holes with EUHFORIA

Journal of Physics: Conference Series, 2020
Abstract Modelling with high accuracy the open magnetic field and the fast solar wind in the heliosphere is essential for space weather forecasting purposes. Primary sources of open magnetic field flux are Coronal Holes (CH), uni-polar regions that appear as dark patches in the solar corona when observed in X-ray and extreme-ultraviolet (
Asvestari, E., Heinemann, S.G., Temmer, M., Pomoell, J., Kilpua, E., Magdalenić, J., Poedts, Stefaan   +6 more
openaire   +2 more sources

On the outflow in an equatorial coronal hole [PDF]

Astronomy & Astrophysics, 2003
We report new observations concerning the source of the fast solar wind by directly comparing Doppler-shift maps of Ne 7 + with charts of the photospheric magnetic field in an equatorial coronal hole, which was observed by SUMER/SOHO and NSO/Kitt Peak on November 5, 1999.
Xia, L., Marsch, E., Curdt, W.
openaire   +2 more sources

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Unipolarity of the Solar Magnetic Field in Equatorial Coronal Holes

The Astrophysical Journal
A study of the unbalanced magnetic polarity distribution of 70 coronal holes was performed. Data from the Helioseismic and Magnetic Imager were used to examine the photospheric line-of-sight magnetic field ( B _LOS ) beneath these coronal holes.
Khagendra Katuwal, R. T. James McAteer
doaj   +1 more source