Results 221 to 230 of about 1,531,913 (378)

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

open access: yesAdvanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin   +18 more
wiley   +1 more source

Relationship Between Coronal Plane Alignment of the Knee Phenotypes and Distal Femoral Rotation. [PDF]

open access: yesJ Clin Med
León-Muñoz VJ   +5 more
europepmc   +1 more source

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He   +5 more
wiley   +1 more source

Coronal plane changes in fixed- versus mobile-bearing unicompartmental knee replacements: Clinical and revision outcomes. [PDF]

open access: yesJ Exp Orthop
Veizi E   +7 more
europepmc   +1 more source

Reconstructing Coherent Functional Landscape From Multi‐Modal Multi‐Slice Spatial Transcriptomics by a Variational Spatial Gaussian Process

open access: yesAdvanced Science, EarlyView.
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang   +3 more
wiley   +1 more source

Distribution and gender-specific differences of coronal plane alignment of healthy knee. [PDF]

open access: yesJ Orthop Surg Res
Phruetthiphat OA   +2 more
europepmc   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang   +11 more
wiley   +1 more source

Reproducibility of coronal plane alignment of the knee (CPAK) using tibia-first restricted inverse kinematic alignment. [PDF]

open access: yesArch Orthop Trauma Surg
Hallak A   +6 more
europepmc   +1 more source

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