, 2017 In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in clinical ...
Išgum, Ivana +7 more
core +2 more sources
Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial [PDF]
, 2013 <p>Background: In patients with acute non–ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective.
Balachandran, Kanarath P. +10 more
core +1 more source
Coronary Atherosclerotic Precursors of Acute Coronary Syndromes
Journal of the American College of Cardiology, 2018 The association of atherosclerotic features with first acute coronary syndromes (ACS) has not accounted for plaque burden.The purpose of this study was to identify atherosclerotic features associated with precursors of ACS.We performed a nested case-control study within a cohort of 25,251 patients undergoing coronary computed tomographic angiography ...
Ran Heo +47 more
openaire +7 more sources
The Acute Responses of Different-sized Coronary Arteries to Testosterone [PDF]
, 2012 Coronary arteries supply blood to the myocardium. The blood flow within the coronary arteries is altered by various compounds produced within the body. Sex hormones such as testosterone are known to cause the relaxation of large coronary arteries.
Madanu, Sampath
core +2 more sources
Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention. [PDF]
, 2017 BackgroundElevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown.Methods and resultsBaseline demographics and 2-year MACE were ...
Ang, Lawrence +7 more
core +1 more source
New England Journal of Medicine, 1999 BACKGROUND Although it is generally accepted that lowering elevated serum levels of low-density lipoprotein (LDL) cholesterol in patients with coronary heart disease is beneficial, there are few data to guide decisions about therapy for patients whose ...
H. Rubins +11 more
semanticscholar +1 more source
Use of Coronary Computed Tomographic Angiography to guide management of patients with coronary disease [PDF]
, 2016 Background In a prospective, multicenter, randomized controlled trial, 4,146 patients were randomized to receive standard care or standard care plus coronary computed tomography angiography (CCTA).
Adam D. Timmis +38 more
core +2 more sources
New England Journal of Medicine, 2004 BACKGROUND C-reactive protein is an inflammatory marker believed to be of value in the prediction of coronary events. We report data from a large study of C-reactive protein and other circulating inflammatory markers, as well as updated meta-analyses, to
J. Danesh +8 more
semanticscholar +1 more source
Feasibility and performance of a device for automatic self-detection of symptomatic acute coronary artery occlusion in outpatients with coronary artery disease : a multicentre observational study [PDF]
, 2019 Background Time delay between onset of symptoms and seeking medical attention is a major determinant of mortality and morbidity in patients with acute coronary artery occlusion. Response time might be reduced by reliable self-detection.
Coeman, Mathieu +11 more
core +2 more sources
Coronary calcium as a predictor of coronary events in four racial or ethnic groups.
New England Journal of Medicine, 2008 BACKGROUND In white populations, computed tomographic measurements of coronary-artery calcium predict coronary heart disease independently of traditional coronary risk factors.
R. Detrano +14 more
semanticscholar +1 more source