Polarization Holographic 4D Phenotyping Reveals Nanoplastic Induced Dysfunction in Zooplankton
Advanced Science, EarlyView.Contaminant‐induced dysfunction in complex aquatic organisms remains difficult to resolve across scales. Polarization Holographic Imaging Microscopy (PHIM) integrates polarization‐sensitive holography with computational volumetric reconstruction for label‐free phenotyping of zooplankton in natural seawater, revealing that nanoplastic stress drives ...
Yuxing Li +8 more
wiley +1 more source
Invasive pressure indices in aortic stenosis: the key role of resting flow after valve replacement
Frontiers in Cardiovascular Medicine, 2023 Muhammad Sabbah +2 more
doaj +1 more source
Triple Total Coronary Occlusions in a Young Adult: Looking Beyond Conventional Atherosclerotic Risk Factors. [PDF]
CureusNaeem J, Begum NM, Amjad F.
europepmc +1 more source
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Sex Differences in the Association Between the Systemic Immune-Inflammation Index and Coronary Lesion Severity in Acute Coronary Syndrome. [PDF]
Immun Inflamm DisHong M +5 more
europepmc +1 more source
Studies on Coronary Circulation in Coronary Sclerosis
Japanese Heart Journal, 1966 openaire +3 more sources
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Advancements in Artificial Intelligence for Enhanced Diagnosis and Prognosis in Cardiac CT: a Comprehensive Review and Future Perspectives. [PDF]
Curr Cardiol RepAdabifirouzjaei F, Budoff M, Nomeli M.
europepmc +1 more source
A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment
Advanced Science, EarlyView.MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu +15 more
wiley +1 more source