Results 71 to 80 of about 1,168,522 (292)

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography

European Heart Journal, 2019
Background Coronary inflammation induces dynamic changes in the balance between water and lipid content in perivascular adipose tissue (PVAT), as captured by perivascular Fat Attenuation Index (FAI) in standard coronary CT angiography (CCTA).
E. Oikonomou, M. Williams, C. Kotanidis, M. Desai, M. Marwan, A. Antonopoulos, K. Thomas, Sheena Thomas, I. Akoumianakis, L. Fan, S. Kesavan, L. Herdman, A. Alashi, E. H. Centeno, M. Lyasheva, B. Griffin, S. Flamm, C. Shirodaria, N. Sabharwal, A. Kelion, M. Dweck, E. V. van Beek, J. Deanfield, J. Hopewell, S. Neubauer, K. Channon, S. Achenbach, D. Newby, C. Antoniades   +28 more
semanticscholar   +1 more source

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

Advanced Science, EarlyView.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang, Song‐Tao Chen, Gang Chen, Le Zhou, Guo‐Liang Zhou, Xin‐Yuan Yu, Long Yuan, Wei‐Qian Deng, Zhen‐Bo Wang, Jing Li, Yi‐Fu Tu, Da‐Wei Zhang, Yuan li, Abdul Sammad, Xiao Zhu, Kai Yin   +15 more
wiley   +1 more source

Unusual case of single coronary artery with anomalous RCA from LAD: The ultimate of cardiac CT

IHJ Cardiovascular Case Reports, 2021
Coronary artery anomalies are found in 0.6%–1.55% of patients who undergo coronary angiography, and the increasing use of diagnostic coronary angiography is unveiling even more complex coronary anomalies.
Keyur Vora, Uday Surana, Alok Ranjan
doaj  

Reduction of radiation dose for coronary computed tomography angiography using prospective electrocardiography-triggered high-pitch acquisition in clinical routine [PDF]

, 2018
Purpose: To evaluate the image quality, radiation exposure, and means of application in a group of patients who underwent coronary computed tomography angiography (CCTA) performed with low-dose prospective electrocardiography (ECG)-triggered acquisition ...
Chaosuwannakit, Narumol, Makarawate, Pattarapong   +1 more
core   +1 more source

Real-world clinical utility and impact on clinical decision-making of coronary computed tomography angiography-derived fractional flow reserve: lessons from the ADVANCE Registry

European Heart Journal, 2018
Aims Non-invasive assessment of stable chest pain patients is a critical determinant of resource utilization and clinical outcomes. Increasingly coronary computed tomography angiography (CCTA) with selective CCTA-derived fractional flow reserve (FFRCT ...
T. Fairbairn, K. Nieman, T. Akasaka, B. Nørgaard, D. Berman, G. Raff, L. Hurwitz-Koweek, G. Pontone, T. Kawasaki, N. Sand, J. Jensen, T. Amano, M. Poon, Kristian A. Øvrehus, J. Sonck, M. Rabbat, S. Mullen, B. de Bruyne, C. Rogers, H. Matsuo, Jeroen J. Bax, J. Leipsic, M. Patel   +22 more
semanticscholar   +1 more source

Machine Learning Framework to Identify Individuals at Risk of Rapid Progression of Coronary Atherosclerosis: From the PARADIGM Registry. [PDF]

, 2020
Background Rapid coronary plaque progression (RPP) is associated with incident cardiovascular events. To date, no method exists for the identification of individuals at risk of RPP at a single point in time.
Al'Aref, Subhi J, Andreini, Daniele, Baskaran, Lohendran, Bax, Jeroen J, Berman, Daniel S, Budoff, Matthew J, Cademartiri, Filippo, Chang, Hyuk-Jae, Chinnaiyan, Kavitha, Choi, Jung Hyun, Chun, Eun Ju, Conte, Edoardo, de Araújo Gonçalves, Pedro, Gottlieb, Ilan, Gransar, Heidi, Hadamitzky, Martin, Han, Donghee, Kim, Yong-Jin, Kolli, Kranthi K, Lee, Byoung Kwon, Lee, Sang-Eun, Leipsic, Jonathon A, Lin, Fay Y, Maffei, Erica, Marques, Hugo, Min, James K, Narula, Jagat, Pontone, Gianluca, Raff, Gilbert L, Samady, Habib, Shaw, Leslee J, Shin, Sangshoon, Stone, Peter, Sung, Ji Min, van Rosendael, Alexander R, Virmani, Renu   +35 more
core  

Coronary angiography in heart failure: when and why? Uncertainty reigns [PDF]

, 2017
No abstract ...
Petrie, Mark C., Rocchiccioli, Paul
core   +1 more source

Anatomical description of malformations of the neck of the left atrial appendage

Clinical Anatomy, EarlyView.
Abstract The recently‐described left atrial appendage (LAA) neck is a truncated cone‐shaped structure that connects the LAA orifice to its lobe. It shows malformations in some cases, but their exact description and clinical significance are unknown. Therefore, the aim of this study was to provide a detailed anatomical and morphometric analysis of LAA ...
Jakub Batko, Rafał Jakiel, Agata Krawczyk–Ożóg, Kacper Jaśkiewicz, Radosław Litwinowicz, Marian Burysz, Marcin Jakiel, Krzysztof Bartuś, Filip Bolechała, Marcin Strona, Mateusz Krystian Hołda   +10 more
wiley   +1 more source

Prevalence of coronary artery fistula in adults performing coronary CT angiography among Egyptian population: a single center study

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background The prevalence of coronary artery fistula (CAF) among Egyptian population is increasing due to widespread availability of coronary CT angiography using high-end CT scanners.
Amr Ahmed Mubarak
doaj   +1 more source