Results 161 to 170 of about 971,148 (308)

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Multi‐omics data mining combined with experimental validation reveals ferroptosis‐ and autophagy‐associated hub genes as diagnostic candidates and immune modulators in atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
Using the GSE225650 dataset, we performed differential expression gene (DEG) screening, Weighted Gene Coexpression Network Analysis (WGCNA), and immune infiltration profiling on atherosclerosis (AS) samples, yielding 104 shared candidate genes. Subsequently, these 104 candidate genes were intersected with ferroptosis‑ and autophagy‑related gene sets ...
Xinou Zheng, Jinling Zheng, Xuezhuang Li, Hua Chen, Li Zhang, Yuqiong Zhao, Yahao Ling   +6 more
wiley   +1 more source

Postpartum Spontaneous Coronary Artery Dissection Involving the Left Main Coronary Artery: A Case Report. [PDF]

Int J Womens Health
Jing H, Zong A, Gong X, Zhang L.
europepmc   +1 more source

Metformin Attenuates Myocardial Ischemia–Reperfusion Injury in Rats by Modulating JNK Pathway and Inhibiting PANoptosis Mechanisms

Cardiovascular Therapeutics
Biao Hou, Xuejian Hou, Liyue Zhang, Tingting Liu, Yang Li, Ran Dong   +5 more
doaj   +1 more source

Lysyl Oxidase Reduces Neutrophil Extravasation in Response to P. aeruginosa in an Infection‐on‐a‐Chip Model

Advanced NanoBiomed Research, EarlyView.
Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo, Tanvi Patil, Josephine Fouts, Eric L. Ginter, Margaret Radke, Hannah K. Weppner, Justin M. Owens, Laurel E. Hind   +7 more
wiley   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

Sex differences in LMR ratio and coronary artery stenosis severity among patients with coronary artery disease. [PDF]

Front Cardiovasc Med
Cao C, Pang W, Lu L, Zhao Y, Lu L, Zhao H.   +5 more
europepmc   +1 more source

Novel lipid parameters for predicting and interpreting the severity of coronary artery lesions in premature coronary artery disease. [PDF]

Front Cardiovasc Med
Song H, Geng Q, Xu Y, Ma Y, Gao J, Sun X, Zhang K, Yan Y, Hou F.   +8 more
europepmc   +1 more source

Applying Fundamental Knowledge of Coronary Artery Anatomy to Diagnose a Coronary Artery Anomaly. [PDF]

JACC Case Rep
Andreou AY.
europepmc   +1 more source

Compositional Characterization, Quality Parameters, and Physicochemical and Bioactive Properties of Pequi (Caryocar brasiliense) Oils From Xingu and Cerrado in Mato Grosso, Brazil

Journal of the American Oil Chemists' Society, EarlyView.
Cerrado oil is richer in MUFA and antioxidant compounds, while Xingu oil shows higher SFA and enhanced oxidative stability, reinforcing the potential of pequi oil as a sustainable bioactive ingredient. ABSTRACT Pequi (Caryocar brasiliense) is a native fruit widely distributed in Brazilian biomes, specially in Cerrado, known for its high oil yield and ...
Dhayna O. Sobral, Patrícia T. Souza, Gabriel S. L. Pereira, Sara Fraga, Maria E. O. Carvalho, Antonio J. A. Meirelles, Eduardo A. C. Batista, Klicia A. Sampaio, Guilherme J. Maximo   +8 more
wiley   +1 more source