Results 81 to 90 of about 971,148 (308)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy [PDF]

, 2018
Background: In patients with ischaemic left ventricular dysfunction, coronary artery bypass surgery (CABG) may decrease mortality, but it is not known whether CABG improves functional capacity.
Al-Khalidi, Hussein R., Cleland, John G.H., Desvigne-Nickens, Patrice, Drazner, Mark H., Jasinski, Marek, Kosevic, Dragana, Leng, Chua Yeow, Mark, Daniel B., Petrie, Mark C., Rajda, Miroslaw, Roy, Ambuj, Rynkiewicz, Andrzej, Stebbins, Amanda, Stewart, Ralph A.H., Szalewska, Dominika, Tungsubutra, Wiwun, Velazquez, Eric J., White, Harvey D.   +17 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Association Between the Malnutrition Status and Adverse Cardiovascular Outcomes in Patients With Obstructive Sleep Apnea and Acute Coronary Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Malnutrition is a critical modifiable risk factor in acute coronary syndrome (ACS). Obstructive sleep apnea (OSA), prevalent in ACS, is associated with adverse outcomes and may also affect nutritional status.
Yixiang Liu, Zekun Zhang, Wenlong Zhao, Yun Zhou, Siyi Li, Yan Yan, Hui Ai, Jingyao Fan, Wei Gong, Shaoping Nie   +9 more
doaj   +1 more source

Prevalence of obstructive coronary artery disease and prognosis in patients with stable symptoms and a zero-coronary calcium score [PDF]

, 2017
© The Author 2017. Published by Oxford University Press on behalf of the European Society of Cardiology.Aims: CT calcium scoring (CTCS) and CT cardiac angiography (CTCA) are widely used in patients with stable chest pain to exclude significant coronary ...
Abidov, Agatston, Al-Mallah, Bittencourt, Budoff, Chaikriangkrai, Cooper, Dewey, Doris, Douglas, Genders, Gottlieb, Hadamitzky, Hulten, Hulten, Lubbers, Meijboom, Min, Montalescot, Ostrom, Pryor, Raff, Rubinshtein, Sarwar, Shaw, Suhny, Takx, The SCOT-HEART Investigators, van Waardhuizen, Villines, Wolk   +30 more
core   +2 more sources

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

Advanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega, Kirthen Shanmuganathan, Laura Poole‐Warren, Susann Beier, Ulises Aregueta Robles   +4 more
wiley   +1 more source

Prevalence of Dyslipidemia among Elementary School Children in Birjand, East of Iran, 2012

Journal of Tehran University Heart Center, 2016
Background: Various studies have indicated that dyslipidemia starts in childhood. There is a relationship between the concentration of blood lipids and atherosclerosis.
Fatemeh Taheri, Toba Kazemi, Bita Bijari, Kokab Namakin, Mahmoud Zardast, Tayyebeh Chahkandi   +5 more
doaj  

Longitudinal changes of obstructive sleep apnea and its impact on cardiovascular outcomes: Results from the Sleep Heart Health Study

Pulmonology
Background Little is known about the longitudinal change in OSA and its impact on cardiovascular outcomes. This study aimed to investigate the association between the OSA changes and cardiovascular outcomes.Methods In the Sleep Heart Health Study (SHHS),
Wenlong Zhao, Jiaqi Du, Yixiang Liu, Yun Zhou, Zekun Zhang, Siyi Li, Yan Yan, Hui Ai, Shaoping Nie, Wei Gong   +9 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Lipid Profiles and Prevalence of Dyslipidemia in Eastern Iranian Adolescents, Birjand, 2012

Iranian Journal of Medical Sciences, 2015
Background: Cardiovascular risk factors begin in childhood and adolescence. This study aimed at assessing serum lipids and prevalence of Dyslipidemia in 11-18 year old students of Birjand.
Fatemeh Taheri, Tayebeh Chahkandi, Toba Kazemi, Bita Bijari, Mahmoud Zardast, Kokab Namakin   +5 more
doaj