Results 171 to 180 of about 47,449 (318)

Pre‐operative anaemia, red blood cell transfusion and mortality after cardiac surgery: a Netherlands Heart Registration mediation analysis

Anaesthesia, EarlyView.
Summary Introduction Pre‐operative anaemia is an established risk factor for mortality after cardiac surgery. The extent to which this risk is mediated by complications related to red blood cell transfusion remains uncertain, particularly across different age groups.
Elisabeth M. Groenewegen, Peter G. Noordzij, Eline Vlot, Saskia Houterman, Toni Klok, Alexander J. Spanjersberg, Maarten Ter Horst, Joost M. A. A. Van Der Maaten, Susanne Eberl, Remco R. Berendsen, R. Arthur Bouwman, Bastiaan M. Gerritse, Thierry V. Scohy, Johannes S. E. Haenen, Jan Hofland, Marieke F. Kingma, Jan Van Klarenbosch, Sander Bramer, Marcel P. J. De Korte, Nicobert E. Wietsma, Olaf L. Cremer, Lizbeth Burgos Ochoa, Thijs C. D. Rettig, on behalf of the NHR Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration   +23 more
wiley   +1 more source

Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets

Anaesthesia, EarlyView.
Summary Introduction Uncertainty remains regarding whether the time of day that cardiac surgery is performed affects postoperative outcomes or if the observed variation can be explained by patient or surgical factors. Methods A secondary analysis of prospectively collected data was conducted to examine the association between time of cardiac surgery ...
Gareth Kitchen, Karen Thomas, Tim Felton, Hannah Durrington, John Blaikley, Stuart W. Grant, David Harrison, Peter McGuigan, Kathryn Rowan, Anthony Wilson, Danny McAuley, Paul Dark   +11 more
wiley   +1 more source

Impact of vasopressin use for postoperative atrial fibrillation in off-pump coronary artery bypass grafting [PDF]

Postoperative atrial fibrillation complicates 15–40% of cardiac surgery cases and is associated with various adverse health outcomes including high mortality.
Aoyama, Tadashi, Fujii, Tasuku, Nishiwaki, Kimitoshi, Nonogaki, Mikio, Yamane, Kochi   +4 more
core  

Postoperative Sleep Interventions and Cardiac Surgery: A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Sleep disturbance is a common issue affecting nearly 78% of cardiothoracic postoperative patients. There are no systematic reviews of randomised controlled trials (RCTs) that evaluate the impact of sleep interventions within this population.
Alexander Lombardo, James Tsimiklis, Ammar Zaka, Alasdair Leslie, Brandon Stretton, Joshua Kovoor, Pramesh Kovoor, Stephen Bacchi, Aashray Gupta   +8 more
wiley   +1 more source

Hemocompatibility Outcomes After Aspirin Withdrawal in Long‐Term HeartMate 3 Left Ventricular Assist Device Patients on Vitamin K Antagonists

Artificial Organs, EarlyView.
Aspirin discontinuation in long‐term, stable Heart Mate 3 LVAD patients maintained on Vitamin K antagonists did not increase hemocompatibility‐related adverse events. These findings support the safety of simplified antithrombotic therapy and extend randomized evidence for aspirin avoidance to the long‐term management of Heart Mate 3 recipients ...
Melanie Arnreiter, Barbara Karner, Hebe Al Asadi, Christina Abd El‐Malak, Christiane Marko, Daniel Zimpfer, Julia Riebandt, Roxana Moayedifar, Thomas Schlöglhofer   +8 more
wiley   +1 more source

Single‐Incision Anterolateral Thoracotomy for LVAD Implantation: A Novel Minimally Invasive Approach

Artificial Organs, EarlyView.
A novel single‐incision anterolateral thoracotomy technique enables complete HeartMate 3 implantation without sternotomy, minimizing surgical trauma and accelerating recovery. This minimally invasive approach is feasible, safe, and may represent a new standard in advanced heart failure surgery.
Ali Saad Merzah, Günes Dogan, Alina Zubarevich, Stefan Rümke, Bastian Schmack, Ezin Deniz, Jasmin Hanke, Arjang Ruhparwar, Jan D. Schmitto, Alexander Weymann   +9 more
wiley   +1 more source

Driveline Infections Among Patients Supported With Left Ventricular Assist Devices: A Single Center Sixteen‐Year Longitudinal Profile

Artificial Organs, EarlyView.
Our study of 1026 LVAD implants revealed HeartWare had lower driveline infection rates than other LVAD types. In addition, severe diabetes was associated with higher risk, while older age and coronary artery disease were linked to a lower risk of driveline infections.
Anh Nguyen, Alexis Shafii, Gabriel Loor, Andrew Civitello, O. Howard Frazier, Todd Rosengart, Kenneth Liao   +6 more
wiley   +1 more source

Hemocompatibility and Long‐Term Outcomes in HeartWare Versus HeartMate II Versus HeartMate 3: Multicenter Real‐World Cohort

Artificial Organs, EarlyView.
Multicenter real‐world cohort (n = 327) comparing LVADs: HeartMate 3 (HM3), HeartMate II (HMII), and HeartWare (HVAD). HM3 showed superior long‐term survival versus legacy devices, driven by fewer hemocompatibility‐related adverse events, especially pump thrombosis and ischemic stroke, while major bleeding was similar across devices.
Hamza H. H. Ben Nasir, Ahmed F. A. Mohammed, Omar Allham, Alish Kolashov, Yusuf Shieba, Lachmandath Tewarie, Bernd Panholzer, Ajay Moza, Assad Haneya, Rashad Zayat   +9 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source