Results 61 to 70 of about 441,765 (218)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Prognostic Value of the Systemic Inflammatory Response Index in Patients with Acute Coronary Syndrome and Obstructive Sleep Apnea

Journal of Inflammation Research
Qian He,1,2 Yun Zhou,1 Xueying Tong,3 Lei Zhen,1 Shutian Shi,1 Wei Gong,1,4 Shaoping Nie1 1Center for Coronary Artery Disease, Division of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China ...
He Q, Zhou Y, Tong X, Zhen L, Shi S, Gong W, Nie S   +6 more
doaj  

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation

Cardiovascular Diabetology, 2018
Background Little is known about factors that affect the composition of contracted blood clots in specific diseases. We investigated the content of polyhedral erythrocytes (polyhedrocytes) formed in blood clots and its determinants in type 2 diabetes ...
Grzegorz Gajos, Aleksander Siniarski, Joanna Natorska, Michał Ząbczyk, Jakub Siudut, Krzysztof Piotr Malinowski, Renata Gołębiowska-Wiatrak, Paweł Rostoff, Anetta Undas   +8 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Association of Weight Change Across Adulthood with Obstructive Sleep Apnea: The Multi-Ethnic Study of Atherosclerosis

Nature and Science of Sleep
Jiaqi Du,1 Wenlong Zhao,1 Yixiang Liu,1 Siyi Li,1 Zekun Zhang,1 Yun Zhou,1 Wenrui Sun,1 Hui Ai,1 Shaoping Nie,1 Wei Gong2 1Center for Coronary Artery Disease, Division of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical ...
Du J, Zhao W, Liu Y, Li S, Zhang Z, Zhou Y, Sun W, Ai H, Nie S, Gong W   +9 more
doaj  

How to Effectively Network During an In-Person Conference: Insights for Junior Researchers

Anatolian Journal of Cardiology, 2023
Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Denizhan Ozdemir, Omar Javed Baqal, Jose Martinez Parachini, Bavana Rangan, Emmanouil Brilakis   +7 more
doaj   +1 more source

Development and validation of a risk prediction model for acute kidney injury in coronary artery disease

BMC Cardiovascular Disorders
Background Acute Kidney Injury (AKI) is a sudden and often reversible condition characterized by rapid kidney function reduction, posing significant risks to coronary artery disease (CAD) patients.
Ming Ye, Chang Liu, Duo Yang, Hai Gao
doaj   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source