Results 71 to 80 of about 485,367 (310)

Miniaturized Devices for On‐the‐Spot Generation of Small‐Diameter Vascular Grafts

Advanced Materials Technologies, EarlyView.
An intracorporeal extrusion device is developed for on‐the‐spot generation of vascular grafts with tunable diameters spanning from 1 to 6 mm. The device uses biomimetic polymers and light, to promptly obtaining biocompatible and high‐burst pressure‐resistant grafts.
Deyanira Hernandez‐Sanchez, Maxime‐Emmanuel Comtois‐Bona, Antony El‐Khoury, Sergio David Garcia Schejtman, Aidan Macadam, Juan‐David Figueroa‐Alegria, Jesus M. Calderon‐Torres, Irene Guzmán‐Soto, Marc Ruel, Erik J. Suuronen, Marcelo Muñoz, Emilio I. Alarcon   +11 more
wiley   +1 more source

Efficacy and safety of drug-coated balloons in chronic total coronary occlusion recanalization: a systematic review and meta-analysis

BMC Cardiovascular Disorders
Background With advancements in chronic total coronary occlusion (CTO) recanalization techniques and concepts, the success rate of recanalization has been steadily increasing.
Yuhao Zhao, Ping Wang, Ze Zheng, Qin Ma, Yuchen Shi, Jinghua Liu   +5 more
doaj   +1 more source

One‐Step Covalent Biofunctionalization of Tubular Constructs Enabled by Surface‐Embedded Radicals

Advanced Materials Technologies, EarlyView.
Uniform covalent biofunctionalization of tubular constructs is achieved in one step using surface‐embedded radicals generated by a novel plasma immersion ion implantation (PIII) technology. This scalable, solvent‐free technology advances bioengineered tubes for tissue engineering and implant applications.
Anyu Zhang, Katazhyna Redzikultsava, Leila Mamizadeh, Bingyan Liu, Jiayan Shao, Junyi Qian, Ziyu Wang, Angus Grant, Shih‐Liang Lee, Richard Tan, Marcela Bilek, Steven G. Wise, Behnam Akhavan   +12 more
wiley   +1 more source

Liquiritin Exerts a Dual Effect on BMSCs Osteogenic Differentiation and Fracture Healing by Activating the ERK/JNK Pathway and Providing Antioxidant Protection

Advanced Therapeutics, EarlyView.
Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.
Haijun Mao, Jing Liu, Juan Feng, Yalikun Yusufu, Lei Yang, Qing Jiang, Minghui Sun   +6 more
wiley   +1 more source

Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation

Cardiovascular Diabetology, 2018
Background Little is known about factors that affect the composition of contracted blood clots in specific diseases. We investigated the content of polyhedral erythrocytes (polyhedrocytes) formed in blood clots and its determinants in type 2 diabetes ...
Grzegorz Gajos, Aleksander Siniarski, Joanna Natorska, Michał Ząbczyk, Jakub Siudut, Krzysztof Piotr Malinowski, Renata Gołębiowska-Wiatrak, Paweł Rostoff, Anetta Undas   +8 more
doaj   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Coronary artery disease in women

Polish Journal of Cardio-Thoracic Surgery, 2018
Cardiovascular diseases, including coronary artery disease (CAD), are the leading cause of death among women and men. Mortality among women is higher than in men. Women more often report atypical anginal symptoms. Non-invasive diagnostic testing of CAD is less sensitive and characteristic in women than in men. Coronary angiography and rewascularization
Dominika Duda-Pyszny, Mariusz Gąsior, Przemysław Trzeciak   +2 more
openaire   +3 more sources

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Prognostic Value of the Systemic Inflammatory Response Index in Patients with Acute Coronary Syndrome and Obstructive Sleep Apnea

Journal of Inflammation Research
Qian He,1,2 Yun Zhou,1 Xueying Tong,3 Lei Zhen,1 Shutian Shi,1 Wei Gong,1,4 Shaoping Nie1 1Center for Coronary Artery Disease, Division of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China ...
He Q, Zhou Y, Tong X, Zhen L, Shi S, Gong W, Nie S   +6 more
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