Results 121 to 130 of about 408,546 (351)

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source

The Prognostic Value of the Coronary Calcium Score for Detecting Significant Coronary Artery Stenosis Based on CT Coronary Angiography in Patients with Coronary Artery Disease

Український журнал серцево-судинної хірургії
Coronary artery disease (CAD) is a leading cause of mortality and disability worldwide. CT coronary angiography is a fast and non-invasive method for diagnosing coronary artery pathology.
Mykhailo S. Ishchenko, Olha R. Romaniuk
doaj  

Single coronary artery anomaly mimicking Coronary Artery Disease (CAD): a case report

Bali Medical Journal
Background: A single coronary artery (SCA) is a rare congenital anatomical anomaly in which only one artery provides blood supply to the entire myocardium. It can be isolated or in conjunction with other congenital cardiac anomalies. Some SCA patients show symptoms of myocardial ischemia to sudden death without evidence of atherosclerosis.
The Veronica Yoshinta, Benny Mulyanto Setiadi, Starry Homenta Rampengan, Edmond Leonard Jim   +3 more
openaire   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort

, 2007
Objectives Interleukin (IL-6) may contribute to the inflammatory response by activating endothelial cells and stimulating the synthesis of fibrinogen. It might thus be important in the pathogenesis of inflammation associated with coronary artery disease (
Cam, Fethi Sirri, Alioglu, Emin, Tengiz, Istemihan, Ercan, Ertugrul, Sekuri, Cevad, Sagcan, Abdi, Berdeli, Afig   +6 more
core   +1 more source

Myocardial ischemia in non-obstructive coronary artery disease : Associations with coronary artery disease morphology and left ventricular hypertrophy [PDF]

, 2020
Background: The underlying mechanisms causing myocardial ischemia in non-obstructive coronary artery disease (CAD) are incompletely understood.
Eskerud, Ingeborg
core  

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Risk Factors for Coronary Artery Diseases: A Study Among Patients With Ischemic Heart Disease in Kerala

Heart India, 2013
Objective : The objective of this study was to analyses the major risk factors for coronary artery disease (CAD) for patients with ischemic heart disease in Kerala.
Cyril James
doaj   +1 more source

Advances and Challenges for GWAS Analysis in Cardiac Diseases: A Focus on Coronary Artery Disease (CAD)

, 2023
The achievement of genome-wide association studies (GWAS) has rapidly progressed our understanding of the etiology of coronary artery disease (CAD). It unlocks new strategies to strengthen the stalling of CAD drug development.
Khan, Shahid Ullah, Saeed, Sumbul, Khalil ur Rehman, Alsuhaibani, Amnah Mohammed, Umber Zaman, Zaman, Umber, Muneeb Ullah, Shahid Ullah Khan, Amnah Mohammed Alsuhaibani, Sumaya Fatima, Refat, Moamen S, Kun Lu, Lu, Kun, Fatima, Sumaya, Sumbul Saeed, Moamen S Refat, Rehman, Khalil ur, Ullah, Muneeb   +17 more
core   +1 more source