Results 261 to 270 of about 408,546 (351)

Association of Circulating Brain-Derived Neurotrophic Factor With Coronary Risk Factors and Coronary Artery Disease in Patients Who Have Undergone Coronary Computed Tomography Angiography. [PDF]

Cardiol Res
Tachibana T, Shiga Y, Miura-Takahashi E, Tashiro K, Tsudome R, Kawahira Y, Kuwano T, Sugihara M, Imaizumi S, Miura SI.   +9 more
europepmc   +1 more source

Cardiovascular Outcomes in a SELECT‐Like Obesity Cohort: Real‐World Insights From the Swedish AROS Database

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background In the SELECT trial, semaglutide reduced major adverse cardiovascular outcomes (MACE) in individuals with overweight or obesity and established cardiovascular disease (CVD) but without diabetes. However, real‐world cardiovascular event rates in comparable populations remain uncharacterised.
Viveca Ritsinger, Josefine Fagerström, Håkan Nero, Thomas Cars, Maria K. Svensson, Anna Norhammar   +5 more
wiley   +1 more source

Carotid Duplex-Derived Markers Across Angiographic Coronary Artery Disease Burden: A Pandemic-Era Real-World Cohort Study. [PDF]

J Clin Med
Aras T, Grigorian A, Tayeh M, Aswad A, Sharkawy M, Almuzakki Z, Dorweiler B, Cernaianu G, Majd P.   +8 more
europepmc   +1 more source

Investigating the Incremental Cost and Utilization Burden of Obstructive Sleep Apnea in Overweight to Severely Obese Patients

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To quantify the incremental economic and utilization burden of comorbid obstructive sleep apnea (OSA) within an overweight to severely obese adult population. Material and Methods This retrospective cohort study utilized 2016–2025 IQVIA PharMetrics Plus Closed Health Plan commercial claims data to identify overweight to severely obese ...
Hyung Seok John Kim, Tien Hoang Tran, Christopher N. Schmickl, Julia F. Slejko   +3 more
wiley   +1 more source

Coronary Artery Disease and Preoperative Coronary Angiography in Elective Thoracic Endovascular Aortic Repair: A Retrospective Cohort Study. [PDF]

J Cardiovasc Dev Dis
Hamiko M, Keswani L, Bayram A, Rondorf T, Spaeth A, Silaschi M, Zimmer S, Probst C, Nickenig G, Ahmad AE, Bakhtiary F, Schahab N.   +11 more
europepmc   +1 more source

Comparative Effects of Emerging Lp(a)‐Lowering Agents and PCSK9‐Directed Therapies on Lipoprotein(a): A Network Meta‐Analysis of Randomised Clinical Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Elevated lipoprotein(a) [Lp(a)] is a genetic ASCVD risk factor that often persists despite intensive LDL‐C lowering. We compared the efficacy and safety of emerging Lp(a)‐targeted therapies (siRNAs, antisense oligonucleotides and an oral assembly inhibitor) with PCSK9‐directed therapies.
Jihad Abu Zayed, Nada A. Al‐Awamleh, Mahmoud Hamad, Mohammad Ibrahim Mahmoud Hdaib, Hazem Ayesh   +4 more
wiley   +1 more source

Coronary Artery Calcium Score Predicts Cardiovascular and Transplant-Related Outcomes in Lung Transplant Recipients. [PDF]

Clin Transplant
Cook DN, Ravindran A, O'Connor S, Huaromo J, Mannem H, Villines TC, Ayers MP.   +6 more
europepmc   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome: Conceptualising an Approach to Health Economic Modelling

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cardiovascular‐kidney‐metabolic (CKM) syndrome has developed into a global public health crisis. Although integrated care is increasingly used to treat patients with CKM, current health economic models fail to capture the value of considering the CKM syndrome as a unified condition.
Volker Foos, Jieling Chen, Phil McEwan, Marc Evans, Pardeep S. Jhund, Paul R. Kalra, Hongtu Zhu, David C. Wheeler, Geraint Roberts, Martin R. Cowie, Andrew H. Briggs   +10 more
wiley   +1 more source

Great debate: the new risk factor-weighted clinical likelihood model is useful to estimate the initial pre-test probability of obstructive coronary artery disease in individuals with suspected chronic coronary syndromes. [PDF]

Eur Heart J
Andreotti F, Thiele H, Thiele H, Vrints C, Jobs A, Winther S, Gröninger J, Capodanno D, Desch S, Nedios S, Gorog DA.   +10 more
europepmc   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source