Results 111 to 120 of about 723,299 (243)

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Coronary artery ectasia : remains a clinical dilemma

, 2010
Coronary artery ectasia (CAE) is defined as localized coronary dilatation that exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times.
Henein, Michael Y,, Zhao, Ying,, Boles, Usama,, Eriksson, Peter,   +3 more
core   +1 more source

Immune Clues to Sinus Blues: Linking Biomarkers to Radiologic Score of Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prolonged inflammatory condition of the nasal and paranasal sinuses that significantly affects quality of life. This study examines the relationship between CRS severity (based on Lund‐Mackay [LM] scores), osteitis, and systemic inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR ...
Lubna Khreesha, Amer Sawalha, Mohammad Darweesh, Qusai Elfadel, Mohammad Alzoubi, Saif Alhawadi, Faris Alsawair, Fares Habboub, Bashar Alsmady, Mohammad Aljarboa, Hashim Alhammouri   +10 more
wiley   +1 more source

Can thrombolytic therapy provide beneficial effects additional to epicardial coronary artery recanalization? A study based on coronary pressure measurement

, 2002
Background Collaterals provide significant blood supply to the myocardium at risk and the presence of a preserved and adequate collateral network may limit microvascular damage during the occlusion of an epicardial coronary artery.
Mercanoglu, F, Yilmaz, E, Oflaz, H, Nisanci, Y, Ozsaruhan, O, Umman, BERRİN, Umman, S, Sezer, M   +7 more
core   +1 more source

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao, Shen Zhan, Gang Fu, Shanshan Guo, Lifang Liu, Wei Liu, Guanghui Xiao, Yuzhu Wang, Lihong Zhang   +8 more
wiley   +1 more source

CORONARY ARTERY ANOMALY. CORONARY-PULMONARY FISTULA [PDF]

, 2019
True coronary and pulmonary fistulas occur quite seldom. Most often this defect is a casual finding at diagnosis of other cardiac diseases. Hemodynamics of this defect is caused by the affected coronary artery shunt into the cardiac chamber or the great ...
A. M. Namitokov, E. I. Zyablova, E. D. Kosmacheva, S. V. Topilina   +3 more
core  

A Systematic Scoping Review of Participant Descriptor, Diversity and Inclusivity Data Reported in Randomised Studies of Post‐Operative Ileus

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Poor reporting of baseline descriptor, diversity and inclusion data is a barrier in surgical research for drawing generalisable conclusions across diverse populations. Post‐operative ileus was used as an exemplar surgical condition to quantify the variation in baseline descriptor, inclusivity and diversity data in randomised ...
Miriam Khalil, Edward Roberts, David G. Jayne, Stephen J. Chapman   +3 more
wiley   +1 more source

Echocardiographic evaluation of coronary artery disease

, 2013
Although the availability and utilization of other noninvasive imaging modalities for the evaluation of coronary artery disease have expanded over the last decade, echocardiography remains the most accessible, cost-effective, and lowest risk imaging ...
Chatzizisis, Ioannis, Murthy, Venkatesh L., Solomon, Scott D.   +2 more
core   +1 more source

Severe Abdominal Aortic Calcification in Pancreaticoduodenectomy: A Vascular Frailty Marker for Selecting Total Pancreatectomy?

ANZ Journal of Surgery, EarlyView.
Severe abdominal aortic calcification on preoperative CT may identify vascular frailty in patients undergoing pancreaticoduodenectomy. Integrated with fistula‐risk scores and frailty assessment, it may inform discussion of standard PD versus planned total pancreatectomy in selected high‐risk patients, while AAC alone is not an indication for TP ...
Mohamed Hajri, Lassad Gharbi, Zied Hadrich, Mohamed Boujemaa   +3 more
wiley   +1 more source