Results 161 to 170 of about 190,857 (302)

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

Impact of Priming Volume Reduction on Hematocrit Retention in Pediatric Cardiopulmonary Bypass: A Retrospective Analysis

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Retrograde autologous priming and venous antegrade priming replace the cardiopulmonary bypass circuit crystalloid with patient blood to mitigate hemodilution. However, their effectiveness in pediatric patients, particularly when analyzed as continuous variables, remains unclear.
Tokimitsu Hibino   +10 more
wiley   +1 more source

Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement: A meta‐analysis

open access: yesPrecision Medical Sciences, EarlyView.
Central illustration: Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement. Abstract Bicuspid aortic valve (BAV) is a common congenital anomaly leading to early aortic stenosis.
Muhammad Huzaifa Ahmed Khan   +12 more
wiley   +1 more source

Association between right-hand 2D:4D ratio and left main coronary artery stenosis in women. [PDF]

open access: yesBMC Cardiovasc Disord
Yıldırım S   +7 more
europepmc   +1 more source

Single‐nucleotide polymorphisms in coronary artery disease: Biological complexity, risk architecture, and implications for precision prevention

open access: yesPrecision Medical Sciences, EarlyView.
This graphical summary highlights the clinical application of single‐nucleotide polymorphisms‐based risk stratification in coronary artery disease. By integrating polygenic risk with clinical assessment, imaging, and preventive strategies, genetic information enables earlier risk identification, optimized screening, and personalized lifestyle and ...
Li Dai   +8 more
wiley   +1 more source

Fractional flow reserve versus intravascular ultrasound guidance for percutaneous coronary intervention in intermediate coronary stenoses: A systematic review and meta‐analysis

open access: yesPrecision Medical Sciences, EarlyView.
Fractional Flow Reserve versus Intravascular Ultrasound for guiding percutaneous coronary intervention in coronary artery disease: A systematic review and meta‐analysis of 5 studies (over 3,900 patients) showing comparable outcomes in MACE, mortality, and target vessel revascularization.
Sanket Patel   +13 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong   +5 more
wiley   +1 more source

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao   +8 more
wiley   +1 more source

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