Results 91 to 100 of about 1,285,317 (373)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Spatiotemporal Super‐Resolution Imaging of Lipid Metabolism Dynamics in Physiological/Pathological Conditions

Angewandte Chemie, EarlyView.
A novel polarity‐sensitive fluorescent probe was developed for the selective targeting of lipid droplets, enabling precise visualization and quantification of lipid metabolism disorders using an integrated STED‐FLIM platform. This probe allows accurate monitoring of lipid metabolism in cellular and pathological contexts, such as atherosclerosis ...
Shixian Cao, Qihang Ding, Caixia Sun, Borbala Codogno, Zhiqiang Liu, Xiaoqiang Yu, Jong Seung Kim, Kang‐Nan Wang   +7 more
wiley   +2 more sources

Prevalence of high blood pressure in primary school children in Birjand-Iran

مجله دانشگاه علوم پزشکی بیرجند, 2013
Background and Aim: High blood pressure is a health problem in children. High blood pressure is a health problem in children, increasing of blood pressure during childhood predisposes children to hypertension in later life stages. In addition, high blood
Mahmood Zrdast, Kokab Namakin, Fatemeh Taheri, Tayyebeh Chahkandi, Bita Bijari, Toba Kazemi   +5 more
doaj  

Computational Modelling of Atherosclerosis

, 2015
Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk from elevated ...
Baldrick, Francina R, McGilligan, Victoria, OKane, Maurice, Parton, Andrew, Watterson, Steven   +4 more
core   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Senile Calcification of the Trachea, Aortic Arch, and Mitral Annulus: An Incidental Finding on Chest X-Ray

Journal of Tehran University Heart Center, 2016
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Mahmood Hosseinzadeh Maleki, Toba Kazemi, Navid Davoody   +2 more
doaj  

Positive Association of Plasma Trimethylamine-N-Oxide and Atherosclerosis in Patient with Acute Coronary Syndrome

Cardiovascular Therapeutics, 2022
Aim. Atherosclerosis is the major cause of acute coronary syndrome (ACS) which is a significant contributor to both morbidity and mortality in the world.
Wanwen Kong, Junyi Ma, Ying Lin, Weiyu Chen   +3 more
doaj   +1 more source

Manifestations of coronary atherosclerosis in young trauma victims—An autopsy study [PDF]

, 1993
Objectives. The aim of this study was to look at the prevalence of coronary atherosclerosis, its severity aid site of involvement in patients 50% narrowing in 20.7% and >75% narrowing in 9%.
Ackerman, Douglas, Johnstone, John, Joseph, Abraham, Kupersmith, Joel, Talley, J.David   +4 more
core   +1 more source

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression

Advanced Science, EarlyView.
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang, Jiong Chen, Zhenhua Zhu, Hong Hu, Qinghui Zhang, Rongrong Jia, Na Wang, Shihao Xiang, Yong Zhou, Yuehong Wang, Ling Xu   +10 more
wiley   +1 more source

Coronary Vasospasm and Coronary Atherosclerosis

Journal of the American College of Cardiology, 2012
In this issue of the Journal , Ong et al. ([1][1]) sought to determine the prevalence of coronary spasm in angina patients with angiographically normal coronary arteries. Of 304 patients with stable angina, 144 (47%) had normal coronary arteries or only minimal irregularities (
MARZILLI, MARIO, Huqi A.
openaire   +4 more sources