Results 151 to 160 of about 1,303,190 (334)

Cardioprotective effects of ranitidine against ischemia-reperfusion injury in mice

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2014
Background and Aim: Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. Increased histamine level in the cardiac tissue has deleterious effects after ischemia-reperfusion occurrence.
Mohsen Foadoddini   +2 more
doaj  

Effectiveness and Safety of Reduced‐Dose Prasugrel in an East Asian Population: PRASFIT‐ACS Emulation Using National Health Insurance Claims Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated the real‐world effectiveness and safety of reduced‐dose prasugrel in
Li‐Wen Huang   +6 more
wiley   +1 more source

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su   +6 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

An intriguing autopsy case of gangrene intestine [PDF]

open access: yes, 2006
Background Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism. Hypothyroidism is a known cause of hyperlipidemia. There is a strong correlation between coronary and mesenteric vessel atherosclerosis.
E., E.Jayashankar   +4 more
core  

Clinicopathologic Correlations in Coronary Atherosclerosis [PDF]

open access: bronze, 1963
Robert Allison   +6 more
openalex   +1 more source

Medical students\\\' perspective of Clinical Educational Environment of Hospitals Affiliated with Birjand University of Medical Sciences, Based on DREEM Model.

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2015
Background and Aim: Clinical education environment is very important to better prepare medical students. The aim of this study is to determine the current status of the of the main parts of the Clinical Hospital of Birjand University of Medical Sciences ...
Seyed Hamidreza Zolfahari, Bita Bijari
doaj  

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu   +3 more
wiley   +1 more source

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